Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19

The pathogenesis of multi-organ dysfunction associated with severe acute SARS-CoV-2 infection remains poorly understood. Endothelial damage and microvascular thrombosis have been identified as drivers of COVID-19 severity, yet the mechanisms underlying these processes remain elusive. Here we show al...

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Detalles Bibliográficos
Autores principales: Druzak, Samuel, Iffrig, Elizabeth, Roberts, Blaine R., Zhang, Tiantian, Fibben, Kirby S., Sakurai, Yumiko, Verkerke, Hans P., Rostad, Christina A., Chahroudi, Ann, Schneider, Frank, Wong, Andrew Kam Ho, Roberts, Anne M., Chandler, Joshua D., Kim, Susan O., Mosunjac, Mario, Mosunjac, Marina, Geller, Rachel, Albizua, Igor, Stowell, Sean R., Arthur, Connie M., Anderson, Evan J., Ivanova, Anna A., Ahn, Jun, Liu, Xueyun, Maner-Smith, Kristal, Bowen, Thomas, Paiardini, Mirko, Bosinger, Steve E., Roback, John D., Kulpa, Deanna A., Silvestri, Guido, Lam, Wilbur A., Ortlund, Eric A., Maier, Cheryl L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073144/
https://www.ncbi.nlm.nih.gov/pubmed/37015925
http://dx.doi.org/10.1038/s41467-023-37269-3

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