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Spatially resolved deconvolution of the fibrotic niche in lung fibrosis

A defining pathological feature of human lung fibrosis is localized tissue heterogeneity, which challenges the interpretation of transcriptomic studies that typically lose spatial information. Here we investigate spatial gene expression in diagnostic tissue using digital profiling technology. We ide...

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Detalles Bibliográficos
Autores principales: Eyres, Michael, Bell, Joseph A., Davies, Elizabeth R., Fabre, Aurelie, Alzetani, Aiman, Jogai, Sanjay, Marshall, Ben G., Johnston, David A., Xu, Zijian, Fletcher, Sophie V., Wang, Yihua, Marshall, Gayle, Davies, Donna E., Offer, Emily, Jones, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073410/
https://www.ncbi.nlm.nih.gov/pubmed/35977489
http://dx.doi.org/10.1016/j.celrep.2022.111230