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Spatially resolved deconvolution of the fibrotic niche in lung fibrosis
A defining pathological feature of human lung fibrosis is localized tissue heterogeneity, which challenges the interpretation of transcriptomic studies that typically lose spatial information. Here we investigate spatial gene expression in diagnostic tissue using digital profiling technology. We ide...
Autores principales: | Eyres, Michael, Bell, Joseph A., Davies, Elizabeth R., Fabre, Aurelie, Alzetani, Aiman, Jogai, Sanjay, Marshall, Ben G., Johnston, David A., Xu, Zijian, Fletcher, Sophie V., Wang, Yihua, Marshall, Gayle, Davies, Donna E., Offer, Emily, Jones, Mark G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073410/ https://www.ncbi.nlm.nih.gov/pubmed/35977489 http://dx.doi.org/10.1016/j.celrep.2022.111230 |
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