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Alteration of neurofilament heavy chain and its phosphoforms reveals early subcellular damage beyond the optic nerve head in glaucoma

BACKGROUND: Retinal ganglion cells (RGCs) axon loss at the site of optic nerve head (ONH) is long believed as the common pathology in glaucoma since different types of glaucoma possessing different characteristic of intraocular pressure, and this damage was only detected at the later stage. METHODS:...

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Detalles Bibliográficos
Autores principales: Zhou, Lan, Lin, Dongyue, Xu, Guihua, Wang, Xiaoyi, Chen, Zilin, Wang, Dingding, Fan, Huiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073422/
https://www.ncbi.nlm.nih.gov/pubmed/37034083
http://dx.doi.org/10.3389/fneur.2023.1091697