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Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model
Liver cancer is a common malignancy of the digestive system. Hepatocellular carcinoma (HCC) accounts for the most majority of these tumors and it has brought a heavy medical burden to underdeveloped countries and regions. Many factors affect the prognosis of HCC patients, however, there is no specif...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073455/ https://www.ncbi.nlm.nih.gov/pubmed/37035138 http://dx.doi.org/10.3389/fonc.2023.1067353 |
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author | Ge, Xin-Yu Sun, Ming-Chen Wang, Tian-Yi Wang, Xi-Min Liu, Gang Yang, Tao Lu, Yi-Ming Wang, Wei |
author_facet | Ge, Xin-Yu Sun, Ming-Chen Wang, Tian-Yi Wang, Xi-Min Liu, Gang Yang, Tao Lu, Yi-Ming Wang, Wei |
author_sort | Ge, Xin-Yu |
collection | PubMed |
description | Liver cancer is a common malignancy of the digestive system. Hepatocellular carcinoma (HCC) accounts for the most majority of these tumors and it has brought a heavy medical burden to underdeveloped countries and regions. Many factors affect the prognosis of HCC patients, however, there is no specific statistical model to predict the survival time of clinical patients. This study derived a risk factor signature of HCC and reliable clinical prediction model by statistically analyzing The Surveillance, Epidemiology, and End Results (SEER) database patient information using an open source package in the python environment. |
format | Online Article Text |
id | pubmed-10073455 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100734552023-04-06 Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model Ge, Xin-Yu Sun, Ming-Chen Wang, Tian-Yi Wang, Xi-Min Liu, Gang Yang, Tao Lu, Yi-Ming Wang, Wei Front Oncol Oncology Liver cancer is a common malignancy of the digestive system. Hepatocellular carcinoma (HCC) accounts for the most majority of these tumors and it has brought a heavy medical burden to underdeveloped countries and regions. Many factors affect the prognosis of HCC patients, however, there is no specific statistical model to predict the survival time of clinical patients. This study derived a risk factor signature of HCC and reliable clinical prediction model by statistically analyzing The Surveillance, Epidemiology, and End Results (SEER) database patient information using an open source package in the python environment. Frontiers Media S.A. 2023-03-22 /pmc/articles/PMC10073455/ /pubmed/37035138 http://dx.doi.org/10.3389/fonc.2023.1067353 Text en Copyright © 2023 Ge, Sun, Wang, Wang, Liu, Yang, Lu and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Ge, Xin-Yu Sun, Ming-Chen Wang, Tian-Yi Wang, Xi-Min Liu, Gang Yang, Tao Lu, Yi-Ming Wang, Wei Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
title | Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
title_full | Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
title_fullStr | Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
title_full_unstemmed | Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
title_short | Analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
title_sort | analysis of risk factors of hepatocellular carcinoma and establishment of a clinical prognosis model |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073455/ https://www.ncbi.nlm.nih.gov/pubmed/37035138 http://dx.doi.org/10.3389/fonc.2023.1067353 |
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