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Improvement of solubility and pharmacokinetic profile of hepatoprotector icariin through complexation with HP-γ-cyclodextrin

Icariin as a hepatoprotector from Herba epimedii can expand the cardiovascular and cerebral blood vessels, promote hematopoietic functions, enhance the immune system and show anti-liver tumor activities. However, its low solubility (0.02 mg/mL) limits its clinical applications as food and medical su...

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Detalles Bibliográficos
Autores principales:	Ding, Yili, Yu, Bo, Zhou, Shuzhen, Ding, Charles, Zhang, Zhiyuan, Xu, Shufeng, Xu, Zhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073486/ https://www.ncbi.nlm.nih.gov/pubmed/37033648 http://dx.doi.org/10.3389/fphar.2023.1138686

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