T790M and Acquired Resistance of Epidermal Growth Factor Receptor to Tyrosine Kinase Inhibitors in Patients with Lung Adenocarcinoma

BACKGROUND: Activating mutations in the epidermal growth factor receptor (EGFR) are initially responsive to tyrosine kinase inhibitors (TKIs), but responses to TKIs is not permanent and drug resistance eventually happens for almost all patients. Subsequent studies found different resistance mechanis...

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Detalles Bibliográficos
Autores principales: Mirtavoos-Mahyari, Hanifeh, Abbasi Dezfouli, Azizollah, Esfahani-Monfared, Zahra, Khosravi, Adnan, Seifi, Sharareh, Sheikhy, Kambiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Research Institute of Tuberculosis and Lung Disease 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073946/
https://www.ncbi.nlm.nih.gov/pubmed/37025321

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