Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections

The objective is to provide a comprehensive overview of the rapidly developing field of the current state of research on in vivo use of hypochlorous acid (HOCl) to aid infection prevention and control, including naso-pharyngeal, alveolar, topical, and systemic HOCl applications. Also, examples are p...

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Autores principales: Boecker, Dirk, Zhang, Zhentian, Breves, Roland, Herth, Felix, Kramer, Axel, Bulitta, Clemens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: German Medical Science GMS Publishing House 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073986/
https://www.ncbi.nlm.nih.gov/pubmed/37034111
http://dx.doi.org/10.3205/dgkh000433
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author Boecker, Dirk
Zhang, Zhentian
Breves, Roland
Herth, Felix
Kramer, Axel
Bulitta, Clemens
author_facet Boecker, Dirk
Zhang, Zhentian
Breves, Roland
Herth, Felix
Kramer, Axel
Bulitta, Clemens
author_sort Boecker, Dirk
collection PubMed
description The objective is to provide a comprehensive overview of the rapidly developing field of the current state of research on in vivo use of hypochlorous acid (HOCl) to aid infection prevention and control, including naso-pharyngeal, alveolar, topical, and systemic HOCl applications. Also, examples are provided of dedicated applications in COVID-19. A brief background of HOCl’s biological and chemical specifics and its physiological role in the innate immune system is provided to understand the effect of in vivo applications in the context of the body’s own physiological defense mechanisms.
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spelling pubmed-100739862023-04-06 Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections Boecker, Dirk Zhang, Zhentian Breves, Roland Herth, Felix Kramer, Axel Bulitta, Clemens GMS Hyg Infect Control Article The objective is to provide a comprehensive overview of the rapidly developing field of the current state of research on in vivo use of hypochlorous acid (HOCl) to aid infection prevention and control, including naso-pharyngeal, alveolar, topical, and systemic HOCl applications. Also, examples are provided of dedicated applications in COVID-19. A brief background of HOCl’s biological and chemical specifics and its physiological role in the innate immune system is provided to understand the effect of in vivo applications in the context of the body’s own physiological defense mechanisms. German Medical Science GMS Publishing House 2023-03-27 /pmc/articles/PMC10073986/ /pubmed/37034111 http://dx.doi.org/10.3205/dgkh000433 Text en Copyright © 2023 Boecker et al. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Boecker, Dirk
Zhang, Zhentian
Breves, Roland
Herth, Felix
Kramer, Axel
Bulitta, Clemens
Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections
title Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections
title_full Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections
title_fullStr Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections
title_full_unstemmed Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections
title_short Antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (HOCl) for prevention or therapeutic support of infections
title_sort antimicrobial efficacy, mode of action and in vivo use of hypochlorous acid (hocl) for prevention or therapeutic support of infections
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10073986/
https://www.ncbi.nlm.nih.gov/pubmed/37034111
http://dx.doi.org/10.3205/dgkh000433
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