Cargando…

Single‐Cell Landscape Highlights Heterogenous Microenvironment, Novel Immune Reaction Patterns, Potential Biomarkers and Unique Therapeutic Strategies of Cervical Squamous Carcinoma, Human Papillomavirus‐Associated (HPVA) and Non‐HPVA Adenocarcinoma

Cervical adenocarcinomas (ADCs), including human papillomavirus (HPV)‐associated (HPVA) and non‐HPVA (NHPVA), though exhibiting a more malignant phenotype and poorer prognosis, are treated identically to squamous cell carcinoma (SCC). This clinical dilemma requires a deeper investigation into their...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qiu, Junjun, Qu, Xinyu, Wang, Yumeng, Guo, Chenyan, Lv, Bin, Jiang, Qian, Su, Wentao, Wang, Li, Hua, Keqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074047/ https://www.ncbi.nlm.nih.gov/pubmed/36725337 http://dx.doi.org/10.1002/advs.202204951

Ejemplares similares

Interactions of Indoleamine 2,3‐dioxygenase‐expressing LAMP3(+) dendritic cells with CD4(+) regulatory T cells and CD8(+) exhausted T cells: synergistically remodeling of the immunosuppressive microenvironment in cervical cancer and therapeutic implications
por: Qu, Xinyu, et al.
Publicado: (2023)

Identification of clinical trait-related small RNA biomarkers with weighted gene co-expression network analysis for personalized medicine in endocervical adenocarcinoma
por: Shi, Zhiwen, et al.
Publicado: (2021)

Identification of a novel six‐gene signature with potential prognostic and therapeutic value in cervical cancer
por: Qu, Xinyu, et al.
Publicado: (2021)

Spatiotemporally deciphering the mysterious mechanism of persistent HPV‐induced malignant transition and immune remodelling from HPV‐infected normal cervix, precancer to cervical cancer: Integrating single‐cell RNA‐sequencing and spatial transcriptome
por: Guo, Chenyan, et al.
Publicado: (2023)

Novel artificial intelligence machine learning approaches to precisely predict survival and site-specific recurrence in cervical cancer: A multi-institutional study
por: Guo, Chenyan, et al.
Publicado: (2021)

Mitochondria-Targeted Mesoporous Organic Silica Nanoplatforms for Overcoming Cisplatin Resistance by Disturbing Mitochondrial Redox Homeostasis
por: Lv, Bin, et al.
Publicado: (2022)

A novel Silva pattern-based model for precisely predicting recurrence in intermediate-risk cervical adenocarcinoma patients
por: Guo, Chenyan, et al.
Publicado: (2022)

Highlights on the Role of KRAS Mutations in Reshaping the Microenvironment of Pancreatic Adenocarcinoma
por: Hafezi, Shirin, et al.
Publicado: (2021)

Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma
por: Zhou, Yan, et al.
Publicado: (2020)

Characteristics, complications, and outcomes of early-stage cervical stump carcinoma: laparoscopy versus laparotomy
por: Lu, Zhiying, et al.
Publicado: (2021)

Heterogeneity and evolution of tumour immune microenvironment in metastatic gastroesophageal adenocarcinoma
por: Wang, Wei, et al.
Publicado: (2022)

Author Correction: Single-cell RNA landscape of intratumoral heterogeneity and immunosuppressive microenvironment in advanced osteosarcoma
por: Zhou, Yan, et al.
Publicado: (2021)

The Heterogeneity in the Landscape of Gene Dominance in Maize is Accompanied by Unique Chromatin Environments
por: Yin, Liangwei, et al.
Publicado: (2022)

Serum Circular FoxO3a Serves as a Novel Prognostic Biomarker in Squamous Cervical Cancer
por: Tang, Xiaoyan, et al.
Publicado: (2020)

The heterogeneous immune landscape between lung adenocarcinoma and squamous carcinoma revealed by single-cell RNA sequencing
por: Wang, Chengdi, et al.
Publicado: (2022)

Targeting CD96 overcomes PD-1 blockade resistance by enhancing CD8+ TIL function in cervical cancer
por: Wang, Yumeng, et al.
Publicado: (2022)

Genetic landscape of prognostic value in pancreas ductal adenocarcinoma microenvironment—reply
por: Pu, Ning, et al.
Publicado: (2020)

Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and transcriptional activities of ECs in CC
por: Li, Chunbo, et al.
Publicado: (2021)

Single Nuclear RNA Sequencing Highlights Intra-Tumoral Heterogeneity and Tumor Microenvironment Complexity in Testicular Embryonic Rhabdomyosarcoma
por: Xu, Xuezheng, et al.
Publicado: (2022)

Highlights of the B-Physics Landscape
por: Fleischer, Robert
Publicado: (2005)

The Study of Sarcoma Microenvironment Heterogeneity Associated With Prognosis Based on an Immunogenomic Landscape Analysis
por: Deng, Jin, et al.
Publicado: (2020)

Examining heterogeneity of stromal cells in tumor microenvironment based on pan-cancer single-cell RNA sequencing data
por: Wang, Wenhui, et al.
Publicado: (2022)

An Intratumor Heterogeneity-Related Signature for Predicting Prognosis, Immune Landscape, and Chemotherapy Response in Colon Adenocarcinoma
por: Liu, Cong, et al.
Publicado: (2022)

Comprehensive Analysis of the Tumor Immune Microenvironment Landscape in Glioblastoma Reveals Tumor Heterogeneity and Implications for Prognosis and Immunotherapy
por: Zhao, Rongrong, et al.
Publicado: (2022)

Multiphasic Heterogeneity of Fibroblasts in the Microenvironment of Pancreatic Ductal Adenocarcinoma: Dissection and the Sum of the Dynamics
por: Ijichi, Hideaki
Publicado: (2022)

Spatial maps of hepatocellular carcinoma transcriptomes highlight an unexplored landscape of heterogeneity and a novel gene signature for survival
por: Zhao, Nan, et al.
Publicado: (2022)

Identification of Prognostic Genes and Immune Landscape Signatures Based on Tumor Microenvironment in Lung Adenocarcinoma
por: Han, Pengkai, et al.
Publicado: (2022)

Prognostic alternative splicing events related splicing factors define the tumor microenvironment and pharmacogenomic landscape in lung adenocarcinoma
por: Liu, Jichang, et al.
Publicado: (2022)

Whole-Genome Resequencing Highlights the Unique Characteristics of Kecai Yaks
por: Kang, Yandong, et al.
Publicado: (2022)

Highlights: Lymphoma microenvironment: Current progress of the tumor microenvironment in lymphoid malignancies
por: Karube, Kennosuke
Publicado: (2021)

The Single‐Cell Landscape of Intratumoral Heterogeneity and The Immunosuppressive Microenvironment in Liver and Brain Metastases of Breast Cancer
por: Zou, Yutian, et al.
Publicado: (2022)

Transcriptomic and glycomic analyses highlight pathway-specific glycosylation alterations unique to Alzheimer’s disease
por: Tang, Xinyu, et al.
Publicado: (2023)

The Unique Beauty of the Subatomic Landscape
por: ’t Hooft, Gerardus
Publicado: (2012)

Editorial: Molecular landscapes of human papillomavirus-related squamous cell carcinoma
por: Shen, Yujie, et al.
Publicado: (2023)

Single-cell RNA-seq reveals transcriptional landscape and intratumor heterogenicity in gallbladder cancer liver metastasis microenvironment
por: Zhang, Yigang, et al.
Publicado: (2021)

Comparative analysis of single-cell transcriptome reveals heterogeneity in the tumor microenvironment of lung adenocarcinoma and brain metastases
por: Liang, Jialu, et al.
Publicado: (2023)

Heterogeneous tumor microenvironment in pancreatic ductal adenocarcinoma: An emerging role of single‐cell analysis
por: Byeon, Sooin, et al.
Publicado: (2023)

Identification of biomarkers complementary to homologous recombination deficiency for improving the clinical outcome of ovarian serous cystadenocarcinoma
por: Shi, Zhiwen, et al.
Publicado: (2021)

The immune cell landscape of glioblastoma patients highlights a myeloid-enriched and immune suppressed microenvironment compared to metastatic brain tumors
por: Musca, Beatrice, et al.
Publicado: (2023)

The landscape of immune microenvironment in lung adenocarcinoma and squamous cell carcinoma based on PD‐L1 expression and tumor‐infiltrating lymphocytes
por: Chen, Lu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ltah1mej2s7qac0cu231i0ffrt