Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation

In human embryos, naive pluripotent cells of the inner cell mass (ICM) generate epiblast, primitive endoderm and trophectoderm (TE) lineages, whence trophoblast cells derive. In vitro, naive pluripotent stem cells (PSCs) retain this potential and efficiently generate trophoblast stem cells (TSCs), w...

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Detalles Bibliográficos
Autores principales: Zorzan, Irene, Betto, Riccardo Massimiliano, Rossignoli, Giada, Arboit, Mattia, Drusin, Andrea, Corridori, Clelia, Martini, Paolo, Martello, Graziano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074076/
https://www.ncbi.nlm.nih.gov/pubmed/36847616
http://dx.doi.org/10.15252/embr.202255235

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