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METTL14 modulates glycolysis to inhibit colorectal tumorigenesis in p53‐wild‐type cells
The frequency of p53 mutations in colorectal cancer (CRC) is approximately 40–50%. A variety of therapies are being developed to target tumors expressing mutant p53. However, potential therapeutic targets for CRC expressing wild‐type p53 are rare. In this study, we show that METTL14 is transcription...
Autores principales: | Hou, Yichao, Zhang, Xintian, Yao, Han, Hou, Lidan, Zhang, Qingwei, Tao, Enwei, Zhu, Xiaoqiang, Jiang, Shanshan, Ren, Yimeng, Hong, Xialu, Lu, Shiyuan, Leng, Xiaoxu, Xie, Yile, Gao, Yaqi, Liang, Yu, Zhong, Ting, Long, Bohan, Fang, Jing‐Yuan, Meng, Xiangjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074077/ https://www.ncbi.nlm.nih.gov/pubmed/36794620 http://dx.doi.org/10.15252/embr.202256325 |
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