Chemical Control of CRISPR Gene Editing via Conditional Diacylation Crosslinking of Guide RNAs

Conditional control of RNA structure and function has emerged as an effective toolkit. Here, a strategy based on a one‐step introduction of diacylation linkers and azide groups on the 2′‐OH of RNA is advance. Selected from eight phosphine reagents, it is found that 2‐(diphenylphosphino)ethylamine ha...

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Detalles Bibliográficos
Autores principales: Lei, Huajun, Zeng, Tianying, Ye, Xiaofang, Fan, Ruochen, Xiong, Wei, Tian, Tian, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074079/
https://www.ncbi.nlm.nih.gov/pubmed/36737854
http://dx.doi.org/10.1002/advs.202206433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074079/
https://www.ncbi.nlm.nih.gov/pubmed/36737854
http://dx.doi.org/10.1002/advs.202206433

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