Boosting the Potential of Chemotherapy in Advanced Breast Cancer Lung Metastasis via Micro‐Combinatorial Hydrogel Particles (Adv. Sci. 10/2023)

Drug Delivery The cover shows multiple metastatic nodules developing at different locations within the lungs. Deformable micro‐combinatorial hydrogel particles (μCGP) are transported by the blood flow, accumulate proximally to the nodules, and release in a sustained fashion thereof the therapeutic c...

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Detalles Bibliográficos
Autores principales: Palange, Anna Lisa, Mascolo, Daniele Di, Ferreira, Miguel, Gawne, Peter J., Spanò, Raffaele, Felici, Alessia, Bono, Luca, Moore, Thomas Lee, Salerno, Marco, Armirotti, Andrea, Decuzzi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Inside Front Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074089/
http://dx.doi.org/10.1002/advs.202370056
Descripción
Sumario:Drug Delivery The cover shows multiple metastatic nodules developing at different locations within the lungs. Deformable micro‐combinatorial hydrogel particles (μCGP) are transported by the blood flow, accumulate proximally to the nodules, and release in a sustained fashion thereof the therapeutic cargo—docetaxel nanomedicines. In an advanced triple negative breast cancer lung metastasis model, μCGP amplify the chemotherapy potential and boost animal survival beyond 5 months. More details can be found in article number 2205223 by Paolo Decuzzi and co‐workers. [Image: see text]

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