Cargando…

Engineered Sensory Nerve Guides Self‐Adaptive Bone Healing via NGF‐TrkA Signaling Pathway

The upstream role of sensory innervation during bone homeostasis is widely underestimated in bone repairing strategies. Herein, a neuromodulation approach is proposed to orchestrate bone defect healing by constructing engineered sensory nerves (eSN) in situ to leverage the adaptation feature of SN d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Zengjie, Wang, Fangqian, Huang, Xin, Sun, Hangxiang, Xu, Jianxiang, Qu, Hao, Yan, Xiaobo, Shi, Wei, Teng, Wangsiyuan, Jin, Xiaoqiang, Shao, Zhenxuan, Zhang, Yongxing, Zhao, Shenzhi, Wu, Yan, Ye, Zhaoming, Yu, Xiaohua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074090/ https://www.ncbi.nlm.nih.gov/pubmed/36725311 http://dx.doi.org/10.1002/advs.202206155

Ejemplares similares

NGF – the TrkA to successful pain treatment
por: Kumar, Vinayak, et al.
Publicado: (2012)

Ectopic trkA expression mediates a NGF survival response in NGF- independent sensory neurons but not in parasympathetic neurons
Publicado: (1993)

Expression of NGF/proNGF and Their Receptors TrkA, p75(NTR) and Sortilin in Melanoma
por: Marsland, Mark, et al.
Publicado: (2022)

QS8: The Roles of the TrkA and p75NTR NGF Receptors in Corneal Wound Healing
por: Tajdaran, Kiana, et al.
Publicado: (2021)

NGF-stimulated retrograde transport of trkA in the mammalian nervous system
Publicado: (1995)

NGF Causes TrkA to Specifically Attract Microtubules to Lipid Rafts
por: Pryor, Shona, et al.
Publicado: (2012)

NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells
por: Ruggeri, P, et al.
Publicado: (2016)

Sensory Neuron-Specific Deletion of Tropomyosin Receptor Kinase A (TrkA) in Mice Abolishes Osteoarthritis (OA) Pain via NGF/TrkA Intervention of Peripheral Sensitization
por: O-Sullivan, InSug, et al.
Publicado: (2022)

Activation of the NGF/TrkA signaling pathway attenuates diabetic erectile dysfunction
por: Hou, Yi, et al.
Publicado: (2017)

Spatiotemporal regulation of angiogenesis/osteogenesis emulating natural bone healing cascade for vascularized bone formation
por: Zhou, Xingzhi, et al.
Publicado: (2021)

Systems Pharmacology of the NGF Signaling Through p75 and TrkA Receptors
por: Toni, T, et al.
Publicado: (2014)

Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling
por: Ye, Mengchen, et al.
Publicado: (2018)

Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling
por: Wong, Hoi Leong Xavier, et al.
Publicado: (2019)

ProNGF, but Not NGF, Switches from Neurotrophic to Apoptotic Activity in Response to Reductions in TrkA Receptor Levels
por: Ioannou, Maria S., et al.
Publicado: (2017)

PDGFR in PDGF-BB/PDGFR Signaling Pathway Does Orchestrates Osteogenesis in a Temporal Manner
por: Wang, Fangqian, et al.
Publicado: (2023)

Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents
por: Canu, Nadia, et al.
Publicado: (2017)

TrkA Co-Receptors: The Janus Face of TrkA?
por: Trouvilliez, Sarah, et al.
Publicado: (2023)

Sprouty4 Is an Endogenous Negative Modulator of TrkA Signaling and Neuronal Differentiation Induced by NGF
por: Alsina, Fernando C., et al.
Publicado: (2012)

Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activity
por: Scarpi, D, et al.
Publicado: (2012)

Low molecular weight, non-peptidic agonists of TrkA receptor with NGF-mimetic activity
por: Scarpi, D, et al.
Publicado: (2012)

NGF-induced TrkA/CD44 association is involved in tumor aggressiveness and resistance to lestaurtinib
por: Aubert, Léo, et al.
Publicado: (2015)

The Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer’s Disease Neuropathology
por: Canu, Nadia, et al.
Publicado: (2017)

hNGF Peptides Elicit the NGF-TrkA Signalling Pathway in Cholinergic Neurons and Retain Full Neurotrophic Activity in the DRG Assay
por: Triaca, Viviana, et al.
Publicado: (2020)

NGF and Neurotrophin-3 Both Activate TrkA on Sympathetic Neurons but Differentially Regulate Survival and Neuritogenesis
por: Belliveau, Daniel J., et al.
Publicado: (1997)

Effects of castration on the expression of the NGF and TrkA in the vas deferens and accessory male genital glands of the rat
por: Squillacioti, C., et al.
Publicado: (2009)

Characterization of NGF, trkA(NGFR), and p75(NTR) in Retina of Mice Lacking Reelin Glycoprotein
por: Balzamino, Bijorn Omar, et al.
Publicado: (2014)

NGF-trkA signaling modulates the analgesic effects of prostatic acid phosphatase in resiniferatoxin-induced neuropathy
por: Wu, Chieh-Hsin, et al.
Publicado: (2016)

NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis
por: Ruggeri, P, et al.
Publicado: (2016)

Expression of Nerve Growth Factor (NGF), TrkA, and p75(NTR) in Developing Human Fetal Teeth
por: Mitsiadis, Thimios A., et al.
Publicado: (2016)

The neurotrophic tyrosine kinase receptor TrkA and its ligand NGF are increased in squamous cell carcinomas of the lung
por: Gao, Fangfang, et al.
Publicado: (2018)

Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons
por: Latina, Valentina, et al.
Publicado: (2017)

NGF-TrkA signaling dictates neural ingrowth and aberrant osteochondral differentiation after soft tissue trauma
por: Lee, Seungyong, et al.
Publicado: (2021)

Effects of pre- and postnatal deletion of the transcription factor NKx2-1 on the expression of NGF, trkA, trkB and p75NTR in mice
por: Ersözlü, S, et al.
Publicado: (2015)

Testicular Expression of NGF, TrkA and p75 During Seasonal Spermatogenesis of the Wild Ground Squirrel (Citellus Dauricus Brandt)
por: Zhang, H., et al.
Publicado: (2015)

Lysophosphatidylcholine enhances NGF-induced MAPK and Akt signals through the extracellular domain of TrkA in PC12 cells()
por: Wuhanqimuge, et al.
Publicado: (2013)

Tailored chondroitin sulfate glycomimetics via a tunable multivalent scaffold for potentiating NGF/TrkA-induced neurogenesis
por: Liu, Pei, et al.
Publicado: (2015)

Effects of Reactive Oxygen and Nitrogen Species on TrkA Expression and Signalling: Implications for proNGF in Aging and Alzheimer’s Disease
por: Kropf, Erika, et al.
Publicado: (2021)

The β-NGF/TrkA Signalling Pathway Is Associated With the Production of Anti-Nucleoprotein IgG in Convalescent COVID-19
por: Usai, Carla, et al.
Publicado: (2022)

Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells
por: Trouvilliez, Sarah, et al.
Publicado: (2022)

NGF Prevents Loss of TrkA/VEGFR2 Cells, and VEGF Isoform Dysregulation in the Retina of Adult Diabetic Rats
por: Fico, Elena, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ojoh5rr3lo72v4dq7hc34ff5jd