Cargando…

Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy

Surgery represents a primary clinical treatment of solid tumors. The high risk of local relapse typically requires frequent hospital visits for postoperative adjuvant therapy. Here, device designs and system integration of a stretchable electronic device for wearable cancer treatment are presented....

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Xiaohui, Wu, Xiaotong, Cao, Shitai, Zhao, Yinfeng, Lin, Yong, Xu, Yurui, Ning, Xinghai, Kong, Desheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074095/
https://www.ncbi.nlm.nih.gov/pubmed/36727804
http://dx.doi.org/10.1002/advs.202205343
Descripción
Sumario:Surgery represents a primary clinical treatment of solid tumors. The high risk of local relapse typically requires frequent hospital visits for postoperative adjuvant therapy. Here, device designs and system integration of a stretchable electronic device for wearable cancer treatment are presented. The soft electronic patch harnesses compliant materials to achieve conformal and stable attachment to the surgical wound. A composite nanotextile dressing is laminated to the electronic patch to allow the on‐demand release of anticancer drugs under electro‐thermal actuation. An additional flexible circuit and a compact battery complete an untethered wearable system to execute remote therapeutic commands from a smartphone. The successful implementation of combined chemothermotherapy to inhibit tumor recurrence demonstrates the promising potential of stretchable electronics for advanced wearable therapies without interfering with daily activities.