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Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy
Surgery represents a primary clinical treatment of solid tumors. The high risk of local relapse typically requires frequent hospital visits for postoperative adjuvant therapy. Here, device designs and system integration of a stretchable electronic device for wearable cancer treatment are presented....
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074095/ https://www.ncbi.nlm.nih.gov/pubmed/36727804 http://dx.doi.org/10.1002/advs.202205343 |
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author | Ma, Xiaohui Wu, Xiaotong Cao, Shitai Zhao, Yinfeng Lin, Yong Xu, Yurui Ning, Xinghai Kong, Desheng |
author_facet | Ma, Xiaohui Wu, Xiaotong Cao, Shitai Zhao, Yinfeng Lin, Yong Xu, Yurui Ning, Xinghai Kong, Desheng |
author_sort | Ma, Xiaohui |
collection | PubMed |
description | Surgery represents a primary clinical treatment of solid tumors. The high risk of local relapse typically requires frequent hospital visits for postoperative adjuvant therapy. Here, device designs and system integration of a stretchable electronic device for wearable cancer treatment are presented. The soft electronic patch harnesses compliant materials to achieve conformal and stable attachment to the surgical wound. A composite nanotextile dressing is laminated to the electronic patch to allow the on‐demand release of anticancer drugs under electro‐thermal actuation. An additional flexible circuit and a compact battery complete an untethered wearable system to execute remote therapeutic commands from a smartphone. The successful implementation of combined chemothermotherapy to inhibit tumor recurrence demonstrates the promising potential of stretchable electronics for advanced wearable therapies without interfering with daily activities. |
format | Online Article Text |
id | pubmed-10074095 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100740952023-04-06 Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy Ma, Xiaohui Wu, Xiaotong Cao, Shitai Zhao, Yinfeng Lin, Yong Xu, Yurui Ning, Xinghai Kong, Desheng Adv Sci (Weinh) Research Articles Surgery represents a primary clinical treatment of solid tumors. The high risk of local relapse typically requires frequent hospital visits for postoperative adjuvant therapy. Here, device designs and system integration of a stretchable electronic device for wearable cancer treatment are presented. The soft electronic patch harnesses compliant materials to achieve conformal and stable attachment to the surgical wound. A composite nanotextile dressing is laminated to the electronic patch to allow the on‐demand release of anticancer drugs under electro‐thermal actuation. An additional flexible circuit and a compact battery complete an untethered wearable system to execute remote therapeutic commands from a smartphone. The successful implementation of combined chemothermotherapy to inhibit tumor recurrence demonstrates the promising potential of stretchable electronics for advanced wearable therapies without interfering with daily activities. John Wiley and Sons Inc. 2023-02-02 /pmc/articles/PMC10074095/ /pubmed/36727804 http://dx.doi.org/10.1002/advs.202205343 Text en © 2023 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Ma, Xiaohui Wu, Xiaotong Cao, Shitai Zhao, Yinfeng Lin, Yong Xu, Yurui Ning, Xinghai Kong, Desheng Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy |
title | Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy |
title_full | Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy |
title_fullStr | Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy |
title_full_unstemmed | Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy |
title_short | Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy |
title_sort | stretchable and skin‐attachable electronic device for remotely controlled wearable cancer therapy |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074095/ https://www.ncbi.nlm.nih.gov/pubmed/36727804 http://dx.doi.org/10.1002/advs.202205343 |
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