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Impact of platelet endothelial aggregation receptor 1 genotypes and DNA methylation on platelet reactivity in patients with recurrent ischemic stroke treated with clopidogrel

INTRODUCTION: The aim of this study is to investigate the role of genetic variation and DNA methylation of PEAR1 rs12041331 in high on-treatment platelet reactivity (HPR) and recurrent ischemic stroke (RIS). METHODS: Genotype, methylation, and mRNA of PEAR1 rs12041331 were detected in patients with...

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Detalles Bibliográficos
Autores principales:	Yang, Jiahui, Bao, Zhengjun, Hu, Guoyu, Luo, Xiaopeng, Zhao, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2023
Materias:	Research Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074304/ https://www.ncbi.nlm.nih.gov/pubmed/37034521 http://dx.doi.org/10.5114/aoms/159180

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