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Co-Crystalline Solid Solution Affords a High-Soluble and Fast-Absorbing Form of Praziquantel

[Image: see text] Praziquantel (PZQ) is a chiral class-II drug, and it is used as a racemate for the treatment of schistosomiasis. The knowledge of several cocrystals with dicarboxylic acids has prompted the realization of solid solutions of PZQ with both enantiomers of malic acid and tartaric acid....

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Detalles Bibliográficos
Autores principales:	Cappuccino, Chiara, Spoletti, Enrico, Renni, Fiammetta, Muntoni, Elisabetta, Keiser, Jennifer, Voinovich, Dario, Perissutti, Beatrice, Lusi, Matteo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074383/ https://www.ncbi.nlm.nih.gov/pubmed/36884008 http://dx.doi.org/10.1021/acs.molpharmaceut.2c00984

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