Cargando…
Fine-tuning the sequential drug release of nano-formulated mutual prodrugs dictates the combination effects
The maintenance of robust ratiometric loading of dual therapeutic agents and fine-tuning release kinetics for consistent in vitro and in vivo optimization of combination effects is vital for discovering new anticancer drug combinations and remains challenging. Smart nanomedicine strategies have been...
Autores principales: | Zhong, Haiping, Li, Xingwei, Yu, Na, Zhang, Xi, Mu, Jingqing, Liu, Tao, Yuan, Bo, Yuan, Xiaoyong, Guo, Shutao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074403/ https://www.ncbi.nlm.nih.gov/pubmed/37035705 http://dx.doi.org/10.1039/d3sc00550j |
Ejemplares similares
-
Modular ketal-linked prodrugs and biomaterials enabled by organocatalytic transisopropenylation of alcohols
por: Yu, Na, et al.
Publicado: (2021) -
Synthesis and Pharmacological Evaluation of Antiinflammatory Mutual Amide Prodrugs
por: Makhija, D. T., et al.
Publicado: (2013) -
FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility
por: Surdo, Nicoletta C., et al.
Publicado: (2017) -
Mutual Amide Prodrug of Etodolac-glucosamine: Synthesis, Characterization and Pharmacological Screening
por: Pandey, Preeti, et al.
Publicado: (2013) -
Glutathione boosting the cytotoxicity of a magnetic platinum(iv) nano-prodrug in tumor cells
por: Zhu, Zhenzhu, et al.
Publicado: (2016)