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Clinical impact of carbapenems in critically ill patients with valproic acid therapy: A propensity-matched analysis
BACKGROUND: Valproic acid (VPA) is one of the most widely used broad-spectrum antiepileptic drugs, and carbapenems (CBPs) remain the drug of choice for severe infection caused by multidrug-resistant bacteria in critically ill patients. The interaction between VPA and CBPs can lead to a rapid depleti...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074422/ https://www.ncbi.nlm.nih.gov/pubmed/37034060 http://dx.doi.org/10.3389/fneur.2023.1069742 |