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Differential splicing of neuronal genes in a Trem2*R47H mouse model mimics alterations associated with Alzheimer’s disease

BACKGROUND: Molecular characterization of late-onset Alzheimer’s disease (LOAD), the leading cause of age-related dementia, has revealed transcripts, proteins, and pathway alterations associated with disease. Assessing these postmortem signatures of LOAD in experimental model systems can further elu...

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Detalles Bibliográficos
Autores principales:	Pandey, Ravi S., Kotredes, Kevin P., Sasner, Michael, Howell, Gareth R., Carter, Gregory W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074678/ https://www.ncbi.nlm.nih.gov/pubmed/37016304 http://dx.doi.org/10.1186/s12864-023-09280-x

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