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DNAfusion: an R/Bioconductor package for increased sensitivity of detecting gene fusions in liquid biopsies
BACKGROUND: EML4-ALK gene fusions are oncogenic drivers in non-small cell lung cancer (NSCLC), and liquid biopsies containing EML4-ALK fragments can be used to study tumor dynamics using next-generation sequencing (NGS). However, the sensitivity of EML4-ALK detection varies between pipelines and ana...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074784/ https://www.ncbi.nlm.nih.gov/pubmed/37016288 http://dx.doi.org/10.1186/s12859-023-05259-3 |