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DNAfusion: an R/Bioconductor package for increased sensitivity of detecting gene fusions in liquid biopsies

BACKGROUND: EML4-ALK gene fusions are oncogenic drivers in non-small cell lung cancer (NSCLC), and liquid biopsies containing EML4-ALK fragments can be used to study tumor dynamics using next-generation sequencing (NGS). However, the sensitivity of EML4-ALK detection varies between pipelines and ana...

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Detalles Bibliográficos
Autores principales:	Maansson, Christoffer Trier, Andersen, Emma Roger, Ulhoi, Maiken Parm, Meldgaard, Peter, Sorensen, Boe Sandahl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074784/ https://www.ncbi.nlm.nih.gov/pubmed/37016288 http://dx.doi.org/10.1186/s12859-023-05259-3

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