Role of T-box transcription factor 3 in gastric cancers

The expression of T-box transcription factor 3 (TBX3) has been identified in various cancers, including gastric cancers. Its role in breast cancers and melanomas has been intensively studied, and its contribution to the progression of cancers through suppressing senescence and promoting epithelial-m...

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Autores principales: Asano, Naoki, Imatani, Akira, Takeuchi, Akio, Saito, Masashi, Jin, Xiao-Yi, Hatta, Waku, Uno, Kaname, Koike, Tomoyuki, Masamune, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074946/
https://www.ncbi.nlm.nih.gov/pubmed/37035275
http://dx.doi.org/10.4291/wjgp.v14.i2.12
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author Asano, Naoki
Imatani, Akira
Takeuchi, Akio
Saito, Masashi
Jin, Xiao-Yi
Hatta, Waku
Uno, Kaname
Koike, Tomoyuki
Masamune, Atsushi
author_facet Asano, Naoki
Imatani, Akira
Takeuchi, Akio
Saito, Masashi
Jin, Xiao-Yi
Hatta, Waku
Uno, Kaname
Koike, Tomoyuki
Masamune, Atsushi
author_sort Asano, Naoki
collection PubMed
description The expression of T-box transcription factor 3 (TBX3) has been identified in various cancers, including gastric cancers. Its role in breast cancers and melanomas has been intensively studied, and its contribution to the progression of cancers through suppressing senescence and promoting epithelial-mesenchymal transition has been reported. Recent reports on the role of TBX3 in gastric cancers have implied its involvement in gastric carcinogenesis. Considering its pivotal role in the initiation and progression of cancers, TBX3 could be a promising therapeutic target for gastric cancers.
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spelling pubmed-100749462023-04-06 Role of T-box transcription factor 3 in gastric cancers Asano, Naoki Imatani, Akira Takeuchi, Akio Saito, Masashi Jin, Xiao-Yi Hatta, Waku Uno, Kaname Koike, Tomoyuki Masamune, Atsushi World J Gastrointest Pathophysiol Minireviews The expression of T-box transcription factor 3 (TBX3) has been identified in various cancers, including gastric cancers. Its role in breast cancers and melanomas has been intensively studied, and its contribution to the progression of cancers through suppressing senescence and promoting epithelial-mesenchymal transition has been reported. Recent reports on the role of TBX3 in gastric cancers have implied its involvement in gastric carcinogenesis. Considering its pivotal role in the initiation and progression of cancers, TBX3 could be a promising therapeutic target for gastric cancers. Baishideng Publishing Group Inc 2023-03-22 2023-03-22 /pmc/articles/PMC10074946/ /pubmed/37035275 http://dx.doi.org/10.4291/wjgp.v14.i2.12 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Minireviews
Asano, Naoki
Imatani, Akira
Takeuchi, Akio
Saito, Masashi
Jin, Xiao-Yi
Hatta, Waku
Uno, Kaname
Koike, Tomoyuki
Masamune, Atsushi
Role of T-box transcription factor 3 in gastric cancers
title Role of T-box transcription factor 3 in gastric cancers
title_full Role of T-box transcription factor 3 in gastric cancers
title_fullStr Role of T-box transcription factor 3 in gastric cancers
title_full_unstemmed Role of T-box transcription factor 3 in gastric cancers
title_short Role of T-box transcription factor 3 in gastric cancers
title_sort role of t-box transcription factor 3 in gastric cancers
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074946/
https://www.ncbi.nlm.nih.gov/pubmed/37035275
http://dx.doi.org/10.4291/wjgp.v14.i2.12
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