Cargando…
Tardive sensory syndrome related to lurasidone: A case report
BACKGROUND: Tardive sensory syndrome (TSS) is a subtype of tardive syndrome (TS), and its etiology is still uncertain. Lurasidone is an atypical antipsychotic that has high affinity for dopamine D2- and serotonergic 5HT2A- and 5-HT7-receptors. CASE SUMMARY: A 52-year-old woman, previously diagnosed...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075022/ https://www.ncbi.nlm.nih.gov/pubmed/37033893 http://dx.doi.org/10.5498/wjp.v13.i3.126 |
_version_ | 1785019834787954688 |
---|---|
author | Lin, Mei-Chun Chang, Yung-Yee Lee, Yu Wang, Liang-Jen |
author_facet | Lin, Mei-Chun Chang, Yung-Yee Lee, Yu Wang, Liang-Jen |
author_sort | Lin, Mei-Chun |
collection | PubMed |
description | BACKGROUND: Tardive sensory syndrome (TSS) is a subtype of tardive syndrome (TS), and its etiology is still uncertain. Lurasidone is an atypical antipsychotic that has high affinity for dopamine D2- and serotonergic 5HT2A- and 5-HT7-receptors. CASE SUMMARY: A 52-year-old woman, previously diagnosed with schizophrenia, and with no history of movement disorders and no sensory paresthesia, had taken lurasidone, initiate dose 40 mg daily then up titration to 120 mg daily, since March 2021, and developed mandibular sensory (pain) paresthesia after 3 mo of administration. After switching from lurasidone to quetiapine, she reported obvious impr-ovement in her mandibular pain. CONCLUSION: It is noteworthy that TSS is a rare subtype of TS, and lurasidone, an atypical antipsychotic, usually has a lower risk of causing TS. In light of the temporal relationship, it is therefore concluded that use of lurasidone might have caused TSS in this patient. We reported this rare case as a reminder that clinicians should adopt a cautious approach when prescribing atypical antipsychotics, so as to prevent TS. |
format | Online Article Text |
id | pubmed-10075022 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-100750222023-04-06 Tardive sensory syndrome related to lurasidone: A case report Lin, Mei-Chun Chang, Yung-Yee Lee, Yu Wang, Liang-Jen World J Psychiatry Case Report BACKGROUND: Tardive sensory syndrome (TSS) is a subtype of tardive syndrome (TS), and its etiology is still uncertain. Lurasidone is an atypical antipsychotic that has high affinity for dopamine D2- and serotonergic 5HT2A- and 5-HT7-receptors. CASE SUMMARY: A 52-year-old woman, previously diagnosed with schizophrenia, and with no history of movement disorders and no sensory paresthesia, had taken lurasidone, initiate dose 40 mg daily then up titration to 120 mg daily, since March 2021, and developed mandibular sensory (pain) paresthesia after 3 mo of administration. After switching from lurasidone to quetiapine, she reported obvious impr-ovement in her mandibular pain. CONCLUSION: It is noteworthy that TSS is a rare subtype of TS, and lurasidone, an atypical antipsychotic, usually has a lower risk of causing TS. In light of the temporal relationship, it is therefore concluded that use of lurasidone might have caused TSS in this patient. We reported this rare case as a reminder that clinicians should adopt a cautious approach when prescribing atypical antipsychotics, so as to prevent TS. Baishideng Publishing Group Inc 2023-03-19 /pmc/articles/PMC10075022/ /pubmed/37033893 http://dx.doi.org/10.5498/wjp.v13.i3.126 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Case Report Lin, Mei-Chun Chang, Yung-Yee Lee, Yu Wang, Liang-Jen Tardive sensory syndrome related to lurasidone: A case report |
title | Tardive sensory syndrome related to lurasidone: A case report |
title_full | Tardive sensory syndrome related to lurasidone: A case report |
title_fullStr | Tardive sensory syndrome related to lurasidone: A case report |
title_full_unstemmed | Tardive sensory syndrome related to lurasidone: A case report |
title_short | Tardive sensory syndrome related to lurasidone: A case report |
title_sort | tardive sensory syndrome related to lurasidone: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075022/ https://www.ncbi.nlm.nih.gov/pubmed/37033893 http://dx.doi.org/10.5498/wjp.v13.i3.126 |
work_keys_str_mv | AT linmeichun tardivesensorysyndromerelatedtolurasidoneacasereport AT changyungyee tardivesensorysyndromerelatedtolurasidoneacasereport AT leeyu tardivesensorysyndromerelatedtolurasidoneacasereport AT wangliangjen tardivesensorysyndromerelatedtolurasidoneacasereport |