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Tardive sensory syndrome related to lurasidone: A case report

BACKGROUND: Tardive sensory syndrome (TSS) is a subtype of tardive syndrome (TS), and its etiology is still uncertain. Lurasidone is an atypical antipsychotic that has high affinity for dopamine D2- and serotonergic 5HT2A- and 5-HT7-receptors. CASE SUMMARY: A 52-year-old woman, previously diagnosed...

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Autores principales: Lin, Mei-Chun, Chang, Yung-Yee, Lee, Yu, Wang, Liang-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075022/
https://www.ncbi.nlm.nih.gov/pubmed/37033893
http://dx.doi.org/10.5498/wjp.v13.i3.126
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author Lin, Mei-Chun
Chang, Yung-Yee
Lee, Yu
Wang, Liang-Jen
author_facet Lin, Mei-Chun
Chang, Yung-Yee
Lee, Yu
Wang, Liang-Jen
author_sort Lin, Mei-Chun
collection PubMed
description BACKGROUND: Tardive sensory syndrome (TSS) is a subtype of tardive syndrome (TS), and its etiology is still uncertain. Lurasidone is an atypical antipsychotic that has high affinity for dopamine D2- and serotonergic 5HT2A- and 5-HT7-receptors. CASE SUMMARY: A 52-year-old woman, previously diagnosed with schizophrenia, and with no history of movement disorders and no sensory paresthesia, had taken lurasidone, initiate dose 40 mg daily then up titration to 120 mg daily, since March 2021, and developed mandibular sensory (pain) paresthesia after 3 mo of administration. After switching from lurasidone to quetiapine, she reported obvious impr-ovement in her mandibular pain. CONCLUSION: It is noteworthy that TSS is a rare subtype of TS, and lurasidone, an atypical antipsychotic, usually has a lower risk of causing TS. In light of the temporal relationship, it is therefore concluded that use of lurasidone might have caused TSS in this patient. We reported this rare case as a reminder that clinicians should adopt a cautious approach when prescribing atypical antipsychotics, so as to prevent TS.
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spelling pubmed-100750222023-04-06 Tardive sensory syndrome related to lurasidone: A case report Lin, Mei-Chun Chang, Yung-Yee Lee, Yu Wang, Liang-Jen World J Psychiatry Case Report BACKGROUND: Tardive sensory syndrome (TSS) is a subtype of tardive syndrome (TS), and its etiology is still uncertain. Lurasidone is an atypical antipsychotic that has high affinity for dopamine D2- and serotonergic 5HT2A- and 5-HT7-receptors. CASE SUMMARY: A 52-year-old woman, previously diagnosed with schizophrenia, and with no history of movement disorders and no sensory paresthesia, had taken lurasidone, initiate dose 40 mg daily then up titration to 120 mg daily, since March 2021, and developed mandibular sensory (pain) paresthesia after 3 mo of administration. After switching from lurasidone to quetiapine, she reported obvious impr-ovement in her mandibular pain. CONCLUSION: It is noteworthy that TSS is a rare subtype of TS, and lurasidone, an atypical antipsychotic, usually has a lower risk of causing TS. In light of the temporal relationship, it is therefore concluded that use of lurasidone might have caused TSS in this patient. We reported this rare case as a reminder that clinicians should adopt a cautious approach when prescribing atypical antipsychotics, so as to prevent TS. Baishideng Publishing Group Inc 2023-03-19 /pmc/articles/PMC10075022/ /pubmed/37033893 http://dx.doi.org/10.5498/wjp.v13.i3.126 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Report
Lin, Mei-Chun
Chang, Yung-Yee
Lee, Yu
Wang, Liang-Jen
Tardive sensory syndrome related to lurasidone: A case report
title Tardive sensory syndrome related to lurasidone: A case report
title_full Tardive sensory syndrome related to lurasidone: A case report
title_fullStr Tardive sensory syndrome related to lurasidone: A case report
title_full_unstemmed Tardive sensory syndrome related to lurasidone: A case report
title_short Tardive sensory syndrome related to lurasidone: A case report
title_sort tardive sensory syndrome related to lurasidone: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075022/
https://www.ncbi.nlm.nih.gov/pubmed/37033893
http://dx.doi.org/10.5498/wjp.v13.i3.126
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