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Identifying novel selective PPO inhibitors through structure-based virtual screening and bio-evaluation

Protoporphyrinogen oxidase (PPO) is a key enzyme in chlorophyll and heme biosynthesis, and the development of its inhibitors is of great importance both in the pharmaceutical and pesticide industries. However, the currently developed PPO inhibitors have insignificant bio-selectivity and have a serio...

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Detalles Bibliográficos
Autores principales:	Zhao, Shan-Shan, Wang, Yu-jie, Tang, Lei, Guo, Bing, Wang, Ling, Zhang, Ji-Quan, Yang, Sheng-Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075065/ https://www.ncbi.nlm.nih.gov/pubmed/37033434 http://dx.doi.org/10.1039/d2ra08006k

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