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Inhibition of autophagy rescues HT22 hippocampal neurons from erastin-induced ferroptosis
Ferroptosis is a regulated form of cell death which is considered an oxidative iron-dependent process. The lipid hydroperoxidase glutathione peroxidase 4 prevents the iron (Fe(2+))-dependent formation of toxic lipid reactive oxygen species. While emerging evidence indicates that inhibition of glutat...
Autores principales: | Hanke, Nora, Rami, Abdelhaq |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075118/ https://www.ncbi.nlm.nih.gov/pubmed/36571361 http://dx.doi.org/10.4103/1673-5374.360246 |
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