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Inhibition of autophagy rescues HT22 hippocampal neurons from erastin-induced ferroptosis

Ferroptosis is a regulated form of cell death which is considered an oxidative iron-dependent process. The lipid hydroperoxidase glutathione peroxidase 4 prevents the iron (Fe(2+))-dependent formation of toxic lipid reactive oxygen species. While emerging evidence indicates that inhibition of glutat...

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Detalles Bibliográficos
Autores principales: Hanke, Nora, Rami, Abdelhaq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075118/
https://www.ncbi.nlm.nih.gov/pubmed/36571361
http://dx.doi.org/10.4103/1673-5374.360246

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