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The GPER Agonist LNS8801 Induces Mitotic Arrest and Apoptosis in Uveal Melanoma Cells

Uveal melanoma is the most common primary intraocular malignancy in adults and has a high incidence of metastatic disease. Current treatments have shown limited clinical activity in patients with uveal melanoma with metastasis and there is an urgent need for new effective therapies. Recent findings...

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Detalles Bibliográficos
Autores principales: Ambrosini, Grazia, Natale, Christopher A., Musi, Elgilda, Garyantes, Tina, Schwartz, Gary K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075232/
https://www.ncbi.nlm.nih.gov/pubmed/37035582
http://dx.doi.org/10.1158/2767-9764.CRC-22-0399