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Case report: Stem cell-based suicide gene therapy mediated by the herpes simplex virus thymidine kinase gene reduces tumor progression in multifocal glioblastoma

INTRODUCTION: The prognosis for glioblastoma multiforme (GBM), a malignant brain tumor, is poor despite recent advancements in treatments. Suicide gene therapy is a therapeutic strategy for cancer that requires a gene to encode a prodrug-activating enzyme which is then transduced into a vector, such...

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Detalles Bibliográficos
Autores principales: Oraee-Yazdani, Saeed, Akhlaghpasand, Mohammadhosein, Rostami, Fatemeh, Golmohammadi, Maryam, Tavanaei, Roozbeh, Shokri, Gelareh, Hafizi, Maryam, Oraee-Yazdani, Maryam, Zali, Ali-Reza, Soleimani, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075310/
https://www.ncbi.nlm.nih.gov/pubmed/37034076
http://dx.doi.org/10.3389/fneur.2023.1060180