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Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study

OBJECTIVE: The study aimed to analyze the temporal trend of congenital syphilis in Brazil in the period from 2008 to 2018 and its spatial distribution in the Immediate Regions of Urban Articulation, and to identify spatial correlations with socioeconomic factors and prenatal care. METHODS: Spatial c...

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Autores principales: Dantas, Janmilli da Costa, Marinho, Cristiane da Silva Ramos, Pinheiro, Yago Tavares, Ferreira, Maria Ângela Fernandes, da Silva, Richardson Augusto Rosendo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075361/
https://www.ncbi.nlm.nih.gov/pubmed/37033177
http://dx.doi.org/10.3389/fped.2023.1109271
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author Dantas, Janmilli da Costa
Marinho, Cristiane da Silva Ramos
Pinheiro, Yago Tavares
Ferreira, Maria Ângela Fernandes
da Silva, Richardson Augusto Rosendo
author_facet Dantas, Janmilli da Costa
Marinho, Cristiane da Silva Ramos
Pinheiro, Yago Tavares
Ferreira, Maria Ângela Fernandes
da Silva, Richardson Augusto Rosendo
author_sort Dantas, Janmilli da Costa
collection PubMed
description OBJECTIVE: The study aimed to analyze the temporal trend of congenital syphilis in Brazil in the period from 2008 to 2018 and its spatial distribution in the Immediate Regions of Urban Articulation, and to identify spatial correlations with socioeconomic factors and prenatal care. METHODS: Spatial correlations between the incidence of congenital syphilis and socioeconomic conditions and access to prenatal care were assessed. This ecological study conducted a time series analysis in Brazil and spatial analysis in 482 Immediate Regions of Urban Articulation. Cases of congenital syphilis reported in the Notifiable Diseases Information System and the Live Birth Information System from January 1, 2008, to December 31, 2018 were included. Socioeconomic conditions (percentage of individuals with inadequate water supply and sanitation) were extracted from the 2010 census, whereas the Live Birth Information System provided data on access to prenatal care (percentage of live births with 1–3 prenatal care appointments). The Joinpoint Regression software performed the temporal trend analysis, while the GeoDa software assessed territorial clusters using the Moran’s I and Local Spatial Association Indicator. RESULTS: The incidence of congenital syphilis showed an upward trend (annual percent change 1 = 26.96; 95% CI: 18.2–36.3; annual percent change 2 = 10.25; 95% CI: 2.7–28.4) and was unevenly distributed across Immediate Regions of Urban Articulation in Brazil (Moran’s I = 0.264, p ≤ 0.05). It also presented a direct spatial correlation with the percentage of individuals with inadequate water supply and sanitation (Moran’s I = 0.02, p ≤ 0.05) and the percentage of live births with 1–3 prenatal care appointments (Moran’s I = 0.03, p ≤ 0.05). CONCLUSION: Agrowth trend of congenital syphilis in Brazil was observed between 2008 and 2018. Moreover, inequalities in socioeconomic conditions and access to prenatal care influenced the spatial distribution of this disease.
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spelling pubmed-100753612023-04-06 Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study Dantas, Janmilli da Costa Marinho, Cristiane da Silva Ramos Pinheiro, Yago Tavares Ferreira, Maria Ângela Fernandes da Silva, Richardson Augusto Rosendo Front Pediatr Pediatrics OBJECTIVE: The study aimed to analyze the temporal trend of congenital syphilis in Brazil in the period from 2008 to 2018 and its spatial distribution in the Immediate Regions of Urban Articulation, and to identify spatial correlations with socioeconomic factors and prenatal care. METHODS: Spatial correlations between the incidence of congenital syphilis and socioeconomic conditions and access to prenatal care were assessed. This ecological study conducted a time series analysis in Brazil and spatial analysis in 482 Immediate Regions of Urban Articulation. Cases of congenital syphilis reported in the Notifiable Diseases Information System and the Live Birth Information System from January 1, 2008, to December 31, 2018 were included. Socioeconomic conditions (percentage of individuals with inadequate water supply and sanitation) were extracted from the 2010 census, whereas the Live Birth Information System provided data on access to prenatal care (percentage of live births with 1–3 prenatal care appointments). The Joinpoint Regression software performed the temporal trend analysis, while the GeoDa software assessed territorial clusters using the Moran’s I and Local Spatial Association Indicator. RESULTS: The incidence of congenital syphilis showed an upward trend (annual percent change 1 = 26.96; 95% CI: 18.2–36.3; annual percent change 2 = 10.25; 95% CI: 2.7–28.4) and was unevenly distributed across Immediate Regions of Urban Articulation in Brazil (Moran’s I = 0.264, p ≤ 0.05). It also presented a direct spatial correlation with the percentage of individuals with inadequate water supply and sanitation (Moran’s I = 0.02, p ≤ 0.05) and the percentage of live births with 1–3 prenatal care appointments (Moran’s I = 0.03, p ≤ 0.05). CONCLUSION: Agrowth trend of congenital syphilis in Brazil was observed between 2008 and 2018. Moreover, inequalities in socioeconomic conditions and access to prenatal care influenced the spatial distribution of this disease. Frontiers Media S.A. 2023-03-22 /pmc/articles/PMC10075361/ /pubmed/37033177 http://dx.doi.org/10.3389/fped.2023.1109271 Text en © 2023 Dantas, Marinho, Pinheiro, Ferreira and da Silva. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Dantas, Janmilli da Costa
Marinho, Cristiane da Silva Ramos
Pinheiro, Yago Tavares
Ferreira, Maria Ângela Fernandes
da Silva, Richardson Augusto Rosendo
Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study
title Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study
title_full Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study
title_fullStr Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study
title_full_unstemmed Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study
title_short Temporal trend and factors associated with spatial distribution of congenital syphilis in Brazil: An ecological study
title_sort temporal trend and factors associated with spatial distribution of congenital syphilis in brazil: an ecological study
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075361/
https://www.ncbi.nlm.nih.gov/pubmed/37033177
http://dx.doi.org/10.3389/fped.2023.1109271
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