Cargando…

Alterations in theta-gamma coupling and sharp wave-ripple, signs of prodromal hippocampal network impairment in the TgF344-AD rat model

Alzheimer’s disease (AD) is a severe neurodegenerative disorder caused by the accumulation of toxic proteins, amyloid-beta (Aβ) and tau, which eventually leads to dementia. Disease-modifying therapies are still lacking, due to incomplete insights into the neuropathological mechanisms of AD. Synaptic...

Descripción completa

Detalles Bibliográficos
Autores principales: van den Berg, Monica, Toen, Daniëlle, Verhoye, Marleen, Keliris, Georgios A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075364/
https://www.ncbi.nlm.nih.gov/pubmed/37032829
http://dx.doi.org/10.3389/fnagi.2023.1081058