A whole blood intracellular cytokine assay optimised for field site studies demonstrates polyfunctionality of CD4+ T cells in acute scrub typhus

BACKGROUND: Assessment of cellular immune responses by combining intracellular cytokine staining and immunophenotyping using flow cytometry enables the simultaneous measurement of T cell phenotype and effector function in response to pathogens and vaccines. The use of whole blood samples rather than...

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Detalles Bibliográficos
Autores principales: Inthawong, Manutsanun, Pinthong, Nattapon, Thaiprakhong, Areerat, Wangrangsimakul, Tri, Sunyakumthorn, Piyanate, Hill, Jennifer, Sonthayanon, Piengchan, Paris, Daniel H., Dunachie, Susanna J., Kronsteiner, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075457/
https://www.ncbi.nlm.nih.gov/pubmed/36961865
http://dx.doi.org/10.1371/journal.pntd.0010905

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