Cargando…

Association of overexpressed carboxyl-terminal amyloid precursor protein in brains with altered glucose metabolism and liver toxicity

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease. The deposition of amyloid plaques mainly composed of amyloid beta (Aβ) is observed in brain regions in AD patients. AD presents with similar pathophysiology to that of metabolic syndrome, including glucose and insulin resistan...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hong, Sungguan, Hong, Seungwoo, Lee, Sung Hoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075522/ https://www.ncbi.nlm.nih.gov/pubmed/37033452 http://dx.doi.org/10.1080/19768354.2023.2197761

Ejemplares similares

Extracellular vesicles: where the amyloid precursor protein carboxyl‐terminal fragments accumulate and amyloid‐β oligomerizes
por: Pérez‐González, Rocío, et al.
Publicado: (2020)

Molecular mechanism of the intramembrane cleavage of the β-carboxyl terminal fragment of amyloid precursor protein by γ-secretase
por: Morishima-Kawashima, Maho
Publicado: (2014)

Lysosomal dysfunction in the brain of a mouse model with intraneuronal accumulation of carboxyl terminal fragments of the amyloid precursor protein
por: Kaur, Gurjinder, et al.
Publicado: (2016)

Overexpression of wild-type human amyloid precursor protein alters GABAergic transmission
por: Kreis, Anna, et al.
Publicado: (2021)

The A673T mutation in the amyloid precursor protein reduces the production of β-amyloid protein from its β-carboxyl terminal fragment in cells
por: Kokawa, Asuka, et al.
Publicado: (2015)

The Exosome Secretory Pathway Transports Amyloid Precursor Protein Carboxyl-terminal Fragments from the Cell into the Brain Extracellular Space
por: Perez-Gonzalez, Rocio, et al.
Publicado: (2012)

TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes
por: Takasugi, Nobumasa, et al.
Publicado: (2018)

Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes
por: Hamilton, D. Lee, et al.
Publicado: (2014)

Overexpression of ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) in boys with cryptorchidism
por: Toliczenko-Bernatowicz, Dorota, et al.
Publicado: (2018)

Amyloid precursor like protein 1 in Idiopathic Normal Pressure hydrocephalus; expanding the knowledge of an altered amyloid metabolism
por: Jeppsson, A, et al.
Publicado: (2015)

Mutations of beta-amyloid precursor protein alter the consequence of Alzheimer’s disease pathogenesis
por: Li, Nuo-Min, et al.
Publicado: (2019)

Generation of Transgenic Cynomolgus Monkeys Overexpressing the Gene for Amyloid-β Precursor Protein
por: Seita, Yasunari, et al.
Publicado: (2020)

Enhanced oncolytic adenoviral production by downregulation of death-domain associated protein and overexpression of precursor terminal protein
por: Lee, Jihyun, et al.
Publicado: (2021)

Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein
por: Pan, Hongyu, et al.
Publicado: (2016)

Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity
por: Cimdins, Kathryn, et al.
Publicado: (2019)

Carboxyl-Terminal Truncations Alter the Activity of the Human α-Galactosidase A
por: Meghdari, Mariam, et al.
Publicado: (2015)

Altered Processing of Amyloid Precursor Protein in Cells Undergoing Apoptosis
por: Fiorelli, Tina, et al.
Publicado: (2013)

Macroautophagy Is Not Directly Involved in the Metabolism of Amyloid Precursor Protein
por: Boland, Barry, et al.
Publicado: (2010)

Amyloid precursor protein and amyloid precursor-like protein 2 in cancer
por: Pandey, Poomy, et al.
Publicado: (2016)

The amyloid precursor protein: beyond amyloid
por: Zheng, Hui, et al.
Publicado: (2006)

EDEM1 Regulates Amyloid Precursor Protein (APP) Metabolism and Amyloid-β Production
por: Nowakowska-Gołacka, Jowita, et al.
Publicado: (2021)

Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer’s disease
por: Boix, Claudia P., et al.
Publicado: (2020)

Overexpression of ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) delays Alzheimer's progression in vivo
por: Zhang, Mingming, et al.
Publicado: (2014)

Hippocampal overexpression of Down syndrome cell adhesion molecule in amyloid precursor protein transgenic mice
por: Jia, Y.L., et al.
Publicado: (2017)

Neuroprotective Effects of Asparagus officinalis Stem Extract in Transgenic Mice Overexpressing Amyloid Precursor Protein
por: Peng, Zhanglong, et al.
Publicado: (2021)

Relevance of amyloid precursor-like protein 2 C-terminal fragments in pancreatic cancer cells
por: PETERS, HALEY L., et al.
Publicado: (2012)

C-terminal fragments of the amyloid precursor protein in cerebrospinal fluid as potential biomarkers for Alzheimer disease
por: García-Ayllón, María-Salud, et al.
Publicado: (2017)

A novel mechanism for the regulation of amyloid precursor protein metabolism
por: Chen, Qi, et al.
Publicado: (2002)

Palmitate and glucose increase amyloid precursor protein in extracellular vesicles: Missing link between metabolic syndrome and Alzheimer's disease
por: Kim, Bhumsoo, et al.
Publicado: (2023)

Carbon Nanomembranes from Aromatic Carboxylate Precursors
por: Dementyev, Petr, et al.
Publicado: (2020)

Targeting apolipoprotein E and N-terminal amyloid β-protein precursor interaction improves cognition and reduces amyloid pathology in Alzheimer’s mice
por: Sawmiller, Darrell, et al.
Publicado: (2023)

Polypropylene microplastics promote metastatic features in human breast cancer
por: Park, Jun Hyung, et al.
Publicado: (2023)

Altered β-Amyloid Precursor Protein Isoforms in Mexican Alzheimer’s Disease Patients
por: Sánchez-González, V. J., et al.
Publicado: (2006)

Moderate blast exposure alters gene expression and levels of amyloid precursor protein
por: Gill, Jessica, et al.
Publicado: (2017)

Glucose Limitation Alters Glutamine Metabolism in MUC1-Overexpressing Pancreatic Cancer Cells
por: Gebregiworgis, Teklab, et al.
Publicado: (2017)

Interactions between amyloid, amyloid precursor protein, and mitochondria
por: Wilkins, Heather M.
Publicado: (2023)

Neuroinflammatory Cytokines Induce Amyloid Beta Neurotoxicity through Modulating Amyloid Precursor Protein Levels/Metabolism
por: Alasmari, Fawaz, et al.
Publicado: (2018)

Altered APP Carboxyl-Terminal Processing Under Ferrous Iron Treatment in PC12 Cells
por: Kim, Chi Hyun, et al.
Publicado: (2013)

Presenilin 1 transgene addition to amyloid precursor protein overexpressing transgenic rats increases amyloid beta 42 levels and results in loss of memory retention
por: Agca, Cansu, et al.
Publicado: (2016)

Justicidin A Reduces β-Amyloid via Inhibiting Endocytosis of β-Amyloid Precursor Protein
por: Chun, Yoon Sun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_p6sv0rsi1e1787ki8472im6spt