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A conserved oligomerization domain in the disordered linker of coronavirus nucleocapsid proteins

The nucleocapsid (N-)protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a key role in viral assembly and scaffolding of the viral RNA. It promotes liquid-liquid phase separation (LLPS), forming dense droplets that support the assembly of ribonucleoprotein particles with as-o...

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Detalles Bibliográficos
Autores principales: Zhao, Huaying, Wu, Di, Hassan, Sergio A., Nguyen, Ai, Chen, Jiji, Piszczek, Grzegorz, Schuck, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075959/
https://www.ncbi.nlm.nih.gov/pubmed/37018390
http://dx.doi.org/10.1126/sciadv.adg6473

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