Therapeutic gene silencing of CKAP5 leads to lethality in genetically unstable cancer cells

The potential of microtubule-associated protein targets for cancer therapeutics remains largely unexplored due to the lack of target-specific agents. Here, we explored the therapeutic potential of targeting cytoskeleton-associated protein 5 (CKAP5), an important microtubule-associated protein, with...

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Detalles Bibliográficos
Autores principales: Chatterjee, Sushmita, Naidu, Gonna Somu, Hazan-Halevy, Inbal, Grobe, Hanna, Ezra, Assaf, Sharma, Preeti, Goldsmith, Meir, Ramishetti, Srinivas, Sprinzak, David, Zaidel-Bar, Ronen, Peer, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10075965/
https://www.ncbi.nlm.nih.gov/pubmed/37018392
http://dx.doi.org/10.1126/sciadv.ade4800

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