UBQLN2 restrains the domesticated retrotransposon PEG10 to maintain neuronal health in ALS

Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive motor neuron dysfunction and loss. A portion of ALS cases are caused by mutation of the proteasome shuttle factor Ubiquilin 2 (UBQLN2), but the molecular pathway leading from UBQLN2 dysfunction to d...

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Detalles Bibliográficos
Autores principales: Black, Holly H, Hanson, Jessica L, Roberts, Julia E, Leslie, Shannon N, Campodonico, Will, Ebmeier, Christopher C, Holling, G Aaron, Tay, Jian Wei, Matthews, Autumn M, Ung, Elizabeth, Lau, Cristina I, Whiteley, Alexandra M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076021/
https://www.ncbi.nlm.nih.gov/pubmed/36951542
http://dx.doi.org/10.7554/eLife.79452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076021/
https://www.ncbi.nlm.nih.gov/pubmed/36951542
http://dx.doi.org/10.7554/eLife.79452

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