Colitis with Hypereosinophilia following the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine: A Case Report with a Literature Review

A 61-year-old man presented with a 7-day history of watery diarrhea and loss of appetite after receiving the second dose of the Pfizer-BioNTech COVID-19 vaccine. Laboratory studies showed significant eosinophilia and an elevated IgE level (white cell count, 18.4×10(9)/L; eosinophil count, 9.5×10(9)/...

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Detalles Bibliográficos
Autores principales: Doman, Tsuyoshi, Saito, Hiroaki, Tanaka, Yukari, Hirasawa, Dai, Endo, Mareyuki, Togo, Daichi, Matsuda, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076129/
https://www.ncbi.nlm.nih.gov/pubmed/36575012
http://dx.doi.org/10.2169/internalmedicine.0518-22
Descripción
Sumario:A 61-year-old man presented with a 7-day history of watery diarrhea and loss of appetite after receiving the second dose of the Pfizer-BioNTech COVID-19 vaccine. Laboratory studies showed significant eosinophilia and an elevated IgE level (white cell count, 18.4×10(9)/L; eosinophil count, 9.5×10(9)/L; and IgE level, 540 IU/L). Symptoms resolved 10 days after vaccination without any steroids or antiallergic medications, and the eosinophil count had also returned to within normal limits 2 months later. Several cases of eosinophilic disorders following receipt of any type of injectable COVID-19 vaccine have been reported, so the etiology should be examined.

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