Colitis with Hypereosinophilia following the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine: A Case Report with a Literature Review

A 61-year-old man presented with a 7-day history of watery diarrhea and loss of appetite after receiving the second dose of the Pfizer-BioNTech COVID-19 vaccine. Laboratory studies showed significant eosinophilia and an elevated IgE level (white cell count, 18.4×10(9)/L; eosinophil count, 9.5×10(9)/...

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Autores principales: Doman, Tsuyoshi, Saito, Hiroaki, Tanaka, Yukari, Hirasawa, Dai, Endo, Mareyuki, Togo, Daichi, Matsuda, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076129/
https://www.ncbi.nlm.nih.gov/pubmed/36575012
http://dx.doi.org/10.2169/internalmedicine.0518-22
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author Doman, Tsuyoshi
Saito, Hiroaki
Tanaka, Yukari
Hirasawa, Dai
Endo, Mareyuki
Togo, Daichi
Matsuda, Tomoki
author_facet Doman, Tsuyoshi
Saito, Hiroaki
Tanaka, Yukari
Hirasawa, Dai
Endo, Mareyuki
Togo, Daichi
Matsuda, Tomoki
author_sort Doman, Tsuyoshi
collection PubMed
description A 61-year-old man presented with a 7-day history of watery diarrhea and loss of appetite after receiving the second dose of the Pfizer-BioNTech COVID-19 vaccine. Laboratory studies showed significant eosinophilia and an elevated IgE level (white cell count, 18.4×10(9)/L; eosinophil count, 9.5×10(9)/L; and IgE level, 540 IU/L). Symptoms resolved 10 days after vaccination without any steroids or antiallergic medications, and the eosinophil count had also returned to within normal limits 2 months later. Several cases of eosinophilic disorders following receipt of any type of injectable COVID-19 vaccine have been reported, so the etiology should be examined.
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spelling pubmed-100761292023-04-06 Colitis with Hypereosinophilia following the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine: A Case Report with a Literature Review Doman, Tsuyoshi Saito, Hiroaki Tanaka, Yukari Hirasawa, Dai Endo, Mareyuki Togo, Daichi Matsuda, Tomoki Intern Med Case Report A 61-year-old man presented with a 7-day history of watery diarrhea and loss of appetite after receiving the second dose of the Pfizer-BioNTech COVID-19 vaccine. Laboratory studies showed significant eosinophilia and an elevated IgE level (white cell count, 18.4×10(9)/L; eosinophil count, 9.5×10(9)/L; and IgE level, 540 IU/L). Symptoms resolved 10 days after vaccination without any steroids or antiallergic medications, and the eosinophil count had also returned to within normal limits 2 months later. Several cases of eosinophilic disorders following receipt of any type of injectable COVID-19 vaccine have been reported, so the etiology should be examined. The Japanese Society of Internal Medicine 2022-12-28 2023-03-15 /pmc/articles/PMC10076129/ /pubmed/36575012 http://dx.doi.org/10.2169/internalmedicine.0518-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Doman, Tsuyoshi
Saito, Hiroaki
Tanaka, Yukari
Hirasawa, Dai
Endo, Mareyuki
Togo, Daichi
Matsuda, Tomoki
Colitis with Hypereosinophilia following the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine: A Case Report with a Literature Review
title Colitis with Hypereosinophilia following the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine: A Case Report with a Literature Review
title_full Colitis with Hypereosinophilia following the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine: A Case Report with a Literature Review
title_fullStr Colitis with Hypereosinophilia following the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine: A Case Report with a Literature Review
title_full_unstemmed Colitis with Hypereosinophilia following the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine: A Case Report with a Literature Review
title_short Colitis with Hypereosinophilia following the Second Dose of the BNT162b2 mRNA COVID-19 Vaccine: A Case Report with a Literature Review
title_sort colitis with hypereosinophilia following the second dose of the bnt162b2 mrna covid-19 vaccine: a case report with a literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076129/
https://www.ncbi.nlm.nih.gov/pubmed/36575012
http://dx.doi.org/10.2169/internalmedicine.0518-22
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