Relapsing Anti-MOG Antibody-associated Disease following COVID-19 Vaccination: A Rare Case Report and Review of the Literature

Anti-myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an autoimmune demyelinating disorder that mainly occurs post-infection or post-vaccination. MOGAD after inoculation with coronavirus disease 2019 (COVID-19) vaccines is rare, and we herein report a rare case of a patient...

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Autores principales: Nakano, Hiroto, Yamaguchi, Kazuyoshi, Hama, Naoyuki, Matsumoto, Yasuko, Shinohara, Moeko, Ide, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076135/
https://www.ncbi.nlm.nih.gov/pubmed/36575011
http://dx.doi.org/10.2169/internalmedicine.0504-22
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author Nakano, Hiroto
Yamaguchi, Kazuyoshi
Hama, Naoyuki
Matsumoto, Yasuko
Shinohara, Moeko
Ide, Hisashi
author_facet Nakano, Hiroto
Yamaguchi, Kazuyoshi
Hama, Naoyuki
Matsumoto, Yasuko
Shinohara, Moeko
Ide, Hisashi
author_sort Nakano, Hiroto
collection PubMed
description Anti-myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an autoimmune demyelinating disorder that mainly occurs post-infection or post-vaccination. MOGAD after inoculation with coronavirus disease 2019 (COVID-19) vaccines is rare, and we herein report a rare case of a patient with MOGAD after vaccination using the Pfizer-BioNTech COVID-19 vaccine (BNT162b2, Pfizer Japan, Tokyo). Our report highlights the fact that MOGAD following inoculation with COVID-19 vaccine may show clinical relapse during reduction of the oral steroid dose, and continuous treatments with immunological agents is needed to prevent disease recurrence.
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spelling pubmed-100761352023-04-06 Relapsing Anti-MOG Antibody-associated Disease following COVID-19 Vaccination: A Rare Case Report and Review of the Literature Nakano, Hiroto Yamaguchi, Kazuyoshi Hama, Naoyuki Matsumoto, Yasuko Shinohara, Moeko Ide, Hisashi Intern Med Case Report Anti-myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an autoimmune demyelinating disorder that mainly occurs post-infection or post-vaccination. MOGAD after inoculation with coronavirus disease 2019 (COVID-19) vaccines is rare, and we herein report a rare case of a patient with MOGAD after vaccination using the Pfizer-BioNTech COVID-19 vaccine (BNT162b2, Pfizer Japan, Tokyo). Our report highlights the fact that MOGAD following inoculation with COVID-19 vaccine may show clinical relapse during reduction of the oral steroid dose, and continuous treatments with immunological agents is needed to prevent disease recurrence. The Japanese Society of Internal Medicine 2022-12-28 2023-03-15 /pmc/articles/PMC10076135/ /pubmed/36575011 http://dx.doi.org/10.2169/internalmedicine.0504-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Nakano, Hiroto
Yamaguchi, Kazuyoshi
Hama, Naoyuki
Matsumoto, Yasuko
Shinohara, Moeko
Ide, Hisashi
Relapsing Anti-MOG Antibody-associated Disease following COVID-19 Vaccination: A Rare Case Report and Review of the Literature
title Relapsing Anti-MOG Antibody-associated Disease following COVID-19 Vaccination: A Rare Case Report and Review of the Literature
title_full Relapsing Anti-MOG Antibody-associated Disease following COVID-19 Vaccination: A Rare Case Report and Review of the Literature
title_fullStr Relapsing Anti-MOG Antibody-associated Disease following COVID-19 Vaccination: A Rare Case Report and Review of the Literature
title_full_unstemmed Relapsing Anti-MOG Antibody-associated Disease following COVID-19 Vaccination: A Rare Case Report and Review of the Literature
title_short Relapsing Anti-MOG Antibody-associated Disease following COVID-19 Vaccination: A Rare Case Report and Review of the Literature
title_sort relapsing anti-mog antibody-associated disease following covid-19 vaccination: a rare case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076135/
https://www.ncbi.nlm.nih.gov/pubmed/36575011
http://dx.doi.org/10.2169/internalmedicine.0504-22
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