Anti-SOX1 Antibody-positive Small-cell Lung Cancer That Triggered Opsoclonus

A 72-year-old woman with opsoclonus visited our hospital and was diagnosed with small-cell lung cancer. Blood tests revealed anti-SOX1 antibodies, so the patient was diagnosed with paraneoplastic opsoclonus-myoclonus syndrome. After steroid pulse therapy was started, chemotherapy of treatment, the o...

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Autores principales: Chiko, Yuki, Sugisaki, Yuka, Miyoshi, Keiji, Morichika, Daisuke, Beika, Yuka, Taniguchi, Akihiko, Ichihara, Eiki, Okada, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076147/
https://www.ncbi.nlm.nih.gov/pubmed/35989271
http://dx.doi.org/10.2169/internalmedicine.0168-22
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author Chiko, Yuki
Sugisaki, Yuka
Miyoshi, Keiji
Morichika, Daisuke
Beika, Yuka
Taniguchi, Akihiko
Ichihara, Eiki
Okada, Toshiaki
author_facet Chiko, Yuki
Sugisaki, Yuka
Miyoshi, Keiji
Morichika, Daisuke
Beika, Yuka
Taniguchi, Akihiko
Ichihara, Eiki
Okada, Toshiaki
author_sort Chiko, Yuki
collection PubMed
description A 72-year-old woman with opsoclonus visited our hospital and was diagnosed with small-cell lung cancer. Blood tests revealed anti-SOX1 antibodies, so the patient was diagnosed with paraneoplastic opsoclonus-myoclonus syndrome. After steroid pulse therapy was started, chemotherapy of treatment, the opsoclonus showed an improving trend. Anti-Ri and anti-Hu antibodies have been reported as autoantibodies associated with neoplastic opsoclonus-myoclonus syndrome; however, there are no such reports concerning anti-SOX1 antibody. Therefore, this is a valuable case.
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spelling pubmed-100761472023-04-06 Anti-SOX1 Antibody-positive Small-cell Lung Cancer That Triggered Opsoclonus Chiko, Yuki Sugisaki, Yuka Miyoshi, Keiji Morichika, Daisuke Beika, Yuka Taniguchi, Akihiko Ichihara, Eiki Okada, Toshiaki Intern Med Case Report A 72-year-old woman with opsoclonus visited our hospital and was diagnosed with small-cell lung cancer. Blood tests revealed anti-SOX1 antibodies, so the patient was diagnosed with paraneoplastic opsoclonus-myoclonus syndrome. After steroid pulse therapy was started, chemotherapy of treatment, the opsoclonus showed an improving trend. Anti-Ri and anti-Hu antibodies have been reported as autoantibodies associated with neoplastic opsoclonus-myoclonus syndrome; however, there are no such reports concerning anti-SOX1 antibody. Therefore, this is a valuable case. The Japanese Society of Internal Medicine 2022-08-20 2023-03-15 /pmc/articles/PMC10076147/ /pubmed/35989271 http://dx.doi.org/10.2169/internalmedicine.0168-22 Text en Copyright © 2023 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Chiko, Yuki
Sugisaki, Yuka
Miyoshi, Keiji
Morichika, Daisuke
Beika, Yuka
Taniguchi, Akihiko
Ichihara, Eiki
Okada, Toshiaki
Anti-SOX1 Antibody-positive Small-cell Lung Cancer That Triggered Opsoclonus
title Anti-SOX1 Antibody-positive Small-cell Lung Cancer That Triggered Opsoclonus
title_full Anti-SOX1 Antibody-positive Small-cell Lung Cancer That Triggered Opsoclonus
title_fullStr Anti-SOX1 Antibody-positive Small-cell Lung Cancer That Triggered Opsoclonus
title_full_unstemmed Anti-SOX1 Antibody-positive Small-cell Lung Cancer That Triggered Opsoclonus
title_short Anti-SOX1 Antibody-positive Small-cell Lung Cancer That Triggered Opsoclonus
title_sort anti-sox1 antibody-positive small-cell lung cancer that triggered opsoclonus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076147/
https://www.ncbi.nlm.nih.gov/pubmed/35989271
http://dx.doi.org/10.2169/internalmedicine.0168-22
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