A dog with extraskeletal osteosarcoma of the salivary glands survived long-term, following surgical resection and adjuvant therapy

A 12-year-old French bulldog presented with a mass on the right lower jaw. Computed tomography revealed that the mass originated from the salivary gland and was not continuous with the right mandible. The mass was surgically removed and subsequently diagnosed as extraskeletal osteosarcoma of the sal...

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Autores principales: UMEDA, Naoki, YAMAZOE, Hinako, WADA, Atsuhito, NAGATA, Katuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2023
Materias:
Surgery
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076193/
https://www.ncbi.nlm.nih.gov/pubmed/36696998
http://dx.doi.org/10.1292/jvms.22-0400
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author UMEDA, Naoki
YAMAZOE, Hinako
WADA, Atsuhito
NAGATA, Katuyuki
author_facet UMEDA, Naoki
YAMAZOE, Hinako
WADA, Atsuhito
NAGATA, Katuyuki
author_sort UMEDA, Naoki
collection PubMed
description A 12-year-old French bulldog presented with a mass on the right lower jaw. Computed tomography revealed that the mass originated from the salivary gland and was not continuous with the right mandible. The mass was surgically removed and subsequently diagnosed as extraskeletal osteosarcoma of the salivary gland following histopathological and immunohistochemical examinations. Although the surgical margin was clear, postoperative adjuvant therapy with nonsteroidal anti-inflammatory drugs (NSAIDs) was initiated. Lung metastasis was observed 249 days after the initial examination; therefore, toceranib was initiated with NSAIDs. The dog died 496 days after the initial examination of this disease progression but had good long-term management with a combination of surgery, NSAIDs, and toceranib.
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spelling pubmed-100761932023-04-07 A dog with extraskeletal osteosarcoma of the salivary glands survived long-term, following surgical resection and adjuvant therapy UMEDA, Naoki YAMAZOE, Hinako WADA, Atsuhito NAGATA, Katuyuki J Vet Med Sci Surgery A 12-year-old French bulldog presented with a mass on the right lower jaw. Computed tomography revealed that the mass originated from the salivary gland and was not continuous with the right mandible. The mass was surgically removed and subsequently diagnosed as extraskeletal osteosarcoma of the salivary gland following histopathological and immunohistochemical examinations. Although the surgical margin was clear, postoperative adjuvant therapy with nonsteroidal anti-inflammatory drugs (NSAIDs) was initiated. Lung metastasis was observed 249 days after the initial examination; therefore, toceranib was initiated with NSAIDs. The dog died 496 days after the initial examination of this disease progression but had good long-term management with a combination of surgery, NSAIDs, and toceranib. The Japanese Society of Veterinary Science 2023-01-24 2023-03 /pmc/articles/PMC10076193/ /pubmed/36696998 http://dx.doi.org/10.1292/jvms.22-0400 Text en ©2023 The Japanese Society of Veterinary Science https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Surgery
UMEDA, Naoki
YAMAZOE, Hinako
WADA, Atsuhito
NAGATA, Katuyuki
A dog with extraskeletal osteosarcoma of the salivary glands survived long-term, following surgical resection and adjuvant therapy
title A dog with extraskeletal osteosarcoma of the salivary glands survived long-term, following surgical resection and adjuvant therapy
title_full A dog with extraskeletal osteosarcoma of the salivary glands survived long-term, following surgical resection and adjuvant therapy
title_fullStr A dog with extraskeletal osteosarcoma of the salivary glands survived long-term, following surgical resection and adjuvant therapy
title_full_unstemmed A dog with extraskeletal osteosarcoma of the salivary glands survived long-term, following surgical resection and adjuvant therapy
title_short A dog with extraskeletal osteosarcoma of the salivary glands survived long-term, following surgical resection and adjuvant therapy
title_sort dog with extraskeletal osteosarcoma of the salivary glands survived long-term, following surgical resection and adjuvant therapy
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076193/
https://www.ncbi.nlm.nih.gov/pubmed/36696998
http://dx.doi.org/10.1292/jvms.22-0400
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