Impaired retinoic acid signaling in cerebral cavernous malformations

The capillary-venous pathology cerebral cavernous malformation (CCM) is caused by loss of CCM1/Krev interaction trapped protein 1 (KRIT1), CCM2/MGC4607, or CCM3/PDCD10 in some endothelial cells. Mutations of CCM genes within the brain vasculature can lead to recurrent cerebral hemorrhages. Pharmacol...

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Detalles Bibliográficos
Autores principales: Grdseloff, Nastasja, Boulday, Gwenola, Rödel, Claudia J., Otten, Cécile, Vannier, Daphné Raphaelle, Cardoso, Cécile, Faurobert, Eva, Dogra, Deepika, Tournier-Lasserve, Elisabeth, Abdelilah-Seyfried, Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076292/
https://www.ncbi.nlm.nih.gov/pubmed/37019926
http://dx.doi.org/10.1038/s41598-023-31905-0

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