Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication

Oncogenic fusions formed through chromosomal rearrangements are hallmarks of childhood cancer that define cancer subtype, predict outcome, persist through treatment, and can be ideal therapeutic targets. However, mechanistic understanding of the etiology of oncogenic fusions remains elusive. Here we...

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Detalles Bibliográficos
Autores principales: Liu, Yanling, Klein, Jonathon, Bajpai, Richa, Dong, Li, Tran, Quang, Kolekar, Pandurang, Smith, Jenny L., Ries, Rhonda E., Huang, Benjamin J., Wang, Yi-Cheng, Alonzo, Todd A., Tian, Liqing, Mulder, Heather L., Shaw, Timothy I., Ma, Jing, Walsh, Michael P., Song, Guangchun, Westover, Tamara, Autry, Robert J., Gout, Alexander M., Wheeler, David A., Wan, Shibiao, Wu, Gang, Yang, Jun J., Evans, William E., Loh, Mignon, Easton, John, Zhang, Jinghui, Klco, Jeffery M., Meshinchi, Soheil, Brown, Patrick A., Pruett-Miller, Shondra M., Ma, Xiaotu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076316/
https://www.ncbi.nlm.nih.gov/pubmed/37019972
http://dx.doi.org/10.1038/s41467-023-37438-4

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