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The association between educational status and colorectal neoplasia: results from a screening cohort
INTRODUCTION: Educational status is used as a proxy for socioeconomic status. While lower levels of education are generally associated with poorer health, the data on the relationship between educational status and colorectal neoplasia is heterogenous. The aim of our study was to examine this relati...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076345/ https://www.ncbi.nlm.nih.gov/pubmed/37017795 http://dx.doi.org/10.1007/s00384-023-04383-z |
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author | Wernly, Sarah Semmler, Georg Schaffler-Schaden, Dagmar Flamm, Maria Aigner, Elmar Datz, Christian Wernly, Bernhard |
author_facet | Wernly, Sarah Semmler, Georg Schaffler-Schaden, Dagmar Flamm, Maria Aigner, Elmar Datz, Christian Wernly, Bernhard |
author_sort | Wernly, Sarah |
collection | PubMed |
description | INTRODUCTION: Educational status is used as a proxy for socioeconomic status. While lower levels of education are generally associated with poorer health, the data on the relationship between educational status and colorectal neoplasia is heterogenous. The aim of our study was to examine this relationship and to adjust the association between educational status and colorectal neoplasia for other health parameters. METHODS: We included 5977 participants undergoing a screening colonoscopy in Austria. We split the cohort into patients with lower (n = 2156), medium (n = 2933), and higher (n = 459) educational status. Multivariable multilevel logistic regression models were fitted to evaluate the association between educational status and the occurrence of any or advanced colorectal neoplasia. We adjusted for age, sex, metabolic syndrome, family history, physical activity, alcohol consumption, and smoking status. RESULTS: We found that the rates of any neoplasia (32%) were similar between the educational strata. However, patients with higher (10%) educational status evidenced significantly higher rates of advanced colorectal neoplasia compared to medium (8%) and lower (7%) education. This association remained statistically significant after multivariable adjustment. The difference was entirely driven by neoplasia in the proximal colon. CONCLUSION: Our study found that higher educational status was associated with a higher prevalence of advanced colorectal neoplasia compared to medium and lower educational status. This finding remained significant even after adjusting for other health parameters. Further research is needed to understand the underlying reasons for the observed difference, especially with regard to the specific anatomical distribution of the observed difference. |
format | Online Article Text |
id | pubmed-10076345 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-100763452023-04-07 The association between educational status and colorectal neoplasia: results from a screening cohort Wernly, Sarah Semmler, Georg Schaffler-Schaden, Dagmar Flamm, Maria Aigner, Elmar Datz, Christian Wernly, Bernhard Int J Colorectal Dis Research INTRODUCTION: Educational status is used as a proxy for socioeconomic status. While lower levels of education are generally associated with poorer health, the data on the relationship between educational status and colorectal neoplasia is heterogenous. The aim of our study was to examine this relationship and to adjust the association between educational status and colorectal neoplasia for other health parameters. METHODS: We included 5977 participants undergoing a screening colonoscopy in Austria. We split the cohort into patients with lower (n = 2156), medium (n = 2933), and higher (n = 459) educational status. Multivariable multilevel logistic regression models were fitted to evaluate the association between educational status and the occurrence of any or advanced colorectal neoplasia. We adjusted for age, sex, metabolic syndrome, family history, physical activity, alcohol consumption, and smoking status. RESULTS: We found that the rates of any neoplasia (32%) were similar between the educational strata. However, patients with higher (10%) educational status evidenced significantly higher rates of advanced colorectal neoplasia compared to medium (8%) and lower (7%) education. This association remained statistically significant after multivariable adjustment. The difference was entirely driven by neoplasia in the proximal colon. CONCLUSION: Our study found that higher educational status was associated with a higher prevalence of advanced colorectal neoplasia compared to medium and lower educational status. This finding remained significant even after adjusting for other health parameters. Further research is needed to understand the underlying reasons for the observed difference, especially with regard to the specific anatomical distribution of the observed difference. Springer Berlin Heidelberg 2023-04-05 2023 /pmc/articles/PMC10076345/ /pubmed/37017795 http://dx.doi.org/10.1007/s00384-023-04383-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Research Wernly, Sarah Semmler, Georg Schaffler-Schaden, Dagmar Flamm, Maria Aigner, Elmar Datz, Christian Wernly, Bernhard The association between educational status and colorectal neoplasia: results from a screening cohort |
title | The association between educational status and colorectal neoplasia: results from a screening cohort |
title_full | The association between educational status and colorectal neoplasia: results from a screening cohort |
title_fullStr | The association between educational status and colorectal neoplasia: results from a screening cohort |
title_full_unstemmed | The association between educational status and colorectal neoplasia: results from a screening cohort |
title_short | The association between educational status and colorectal neoplasia: results from a screening cohort |
title_sort | association between educational status and colorectal neoplasia: results from a screening cohort |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076345/ https://www.ncbi.nlm.nih.gov/pubmed/37017795 http://dx.doi.org/10.1007/s00384-023-04383-z |
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