Aldose reductase inhibition decelerates optic nerve degeneration by alleviating retinal microglia activation

As part of the central nervous system (CNS), retinal ganglion cells (RGCs) and their axons are the only neurons in the retina that transmit visual signals from the eye to the brain via the optic nerve (ON). Unfortunately, they do not regenerate upon injury in mammals. In ON trauma, retinal microglia...

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Detalles Bibliográficos
Autores principales: Rao, Mishal, Huang, Yu-Kai, Liu, Chia-Chun, Meadows, Chandler, Cheng, Hui-Chun, Zhou, Mengli, Chen, Yu-Chih, Xia, Xin, Goldberg, Jeffrey L., Williams, Andrew M., Kuwajima, Takaaki, Chang, Kun-Che
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076364/
https://www.ncbi.nlm.nih.gov/pubmed/37019993
http://dx.doi.org/10.1038/s41598-023-32702-5

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