A severe neurodegenerative disease with Lewy bodies and a mutation in the glucocerebrosidase gene

Several heterozygous variants of the glucocerebrosidase gene (GBA1) have been reported to increase the risk of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). GBA1-associated PD has been reported to be more severe than idiopathic PD, and more deleterious variants are associated with mo...

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Detalles Bibliográficos
Autores principales: Sipilä, Jussi O. T., Kytövuori, Laura, Rauramaa, Tuomas, Rauhamaa, Hugo, Kaasinen, Valtteri, Majamaa, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076383/
https://www.ncbi.nlm.nih.gov/pubmed/37019925
http://dx.doi.org/10.1038/s41531-023-00501-4

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