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[(18)F]FE-PE2I DAT correlates with Parkinson’s disease duration, stage, and rigidity/bradykinesia scores: a PET radioligand validation study

BACKGROUND: Correlations between dopamine transporter (DAT) availability and Parkinson’s disease (PD) motor symptoms vary depending on the imaging modality, choice of regions of interest and clinical measures. We aimed to validate the PET radioligand [(18)F]FE-PE2I as a clinical biomarker in PD, hyp...

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Detalles Bibliográficos
Autores principales: Kerstens, Vera S., Fazio, Patrik, Sundgren, Mathias, Halldin, Christer, Svenningsson, Per, Varrone, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076455/
https://www.ncbi.nlm.nih.gov/pubmed/37017878
http://dx.doi.org/10.1186/s13550-023-00974-7