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The effect of single-cell knockout of Fragile X Messenger Ribonucleoprotein on synaptic structural plasticity
Fragile X Syndrome (FXS) is the best-known form of inherited intellectual disability caused by the loss-of-function mutation in a single gene. The FMR1 gene mutation abolishes the expression of Fragile X Messenger Ribonucleoprotein (FMRP), which regulates the expression of many synaptic proteins. Co...
Autores principales: | Gredell, Marie, Lu, Ju, Zuo, Yi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076639/ https://www.ncbi.nlm.nih.gov/pubmed/37035256 http://dx.doi.org/10.3389/fnsyn.2023.1135479 |
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