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The immunologically high-risk kidney recipient in the early post-COVID-19 period. To do or not to do? A case report

Kidney transplantation is nowadays the treatment of choice for end-stage kidney disease (ESKD), and it is the most performed organ transplantation. During the COVID-19 pandemic, kidney-transplant recipients appeared to be at higher risk of morbidity and mortality due to severe forms of illness. The...

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Autores principales: Antal, Oana, Daciana Elec, Alina, Muntean, Adriana, Moisoiu, Tudor, Melinte, Razvan Marian, Elec, Florin Ioan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076652/
https://www.ncbi.nlm.nih.gov/pubmed/37035338
http://dx.doi.org/10.3389/fmed.2023.1147835
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author Antal, Oana
Daciana Elec, Alina
Muntean, Adriana
Moisoiu, Tudor
Melinte, Razvan Marian
Elec, Florin Ioan
author_facet Antal, Oana
Daciana Elec, Alina
Muntean, Adriana
Moisoiu, Tudor
Melinte, Razvan Marian
Elec, Florin Ioan
author_sort Antal, Oana
collection PubMed
description Kidney transplantation is nowadays the treatment of choice for end-stage kidney disease (ESKD), and it is the most performed organ transplantation. During the COVID-19 pandemic, kidney-transplant recipients appeared to be at higher risk of morbidity and mortality due to severe forms of illness. The result was a decrease in the number of solid organs transplants worldwide, with patients' reduced chance of receiving transplants. The best timing for surgery after COVID-19 infection is still controversial since most of the available data come from study periods with zero or low prevalence of vaccination and COVID-19 variants with high mortality rates. The American Society of Anesthesiologists (ASA) and the Anesthesia Patient Safety Foundation (APSF) Joint Statement on Elective Surgery/Procedures and Anesthesia for Patients after COVID-19 Infection states that elective surgery should be delayed for 7 weeks after a SARS-CoV-2 infection in unvaccinated patients while making no clear statement for vaccinated ones, or those which have already been infected with the virus. Kidney transplant, as opposed to tissue transplant, is not an elective surgery, so the question raised is whether to do it or not. We present the case of a hyper-immunized 47-year-old male patient with end-stage chronic kidney disease who received a second kidney transplant, despite having a mild SARS-COV 2 infection just 2 weeks before his transplantation surgery.
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spelling pubmed-100766522023-04-07 The immunologically high-risk kidney recipient in the early post-COVID-19 period. To do or not to do? A case report Antal, Oana Daciana Elec, Alina Muntean, Adriana Moisoiu, Tudor Melinte, Razvan Marian Elec, Florin Ioan Front Med (Lausanne) Medicine Kidney transplantation is nowadays the treatment of choice for end-stage kidney disease (ESKD), and it is the most performed organ transplantation. During the COVID-19 pandemic, kidney-transplant recipients appeared to be at higher risk of morbidity and mortality due to severe forms of illness. The result was a decrease in the number of solid organs transplants worldwide, with patients' reduced chance of receiving transplants. The best timing for surgery after COVID-19 infection is still controversial since most of the available data come from study periods with zero or low prevalence of vaccination and COVID-19 variants with high mortality rates. The American Society of Anesthesiologists (ASA) and the Anesthesia Patient Safety Foundation (APSF) Joint Statement on Elective Surgery/Procedures and Anesthesia for Patients after COVID-19 Infection states that elective surgery should be delayed for 7 weeks after a SARS-CoV-2 infection in unvaccinated patients while making no clear statement for vaccinated ones, or those which have already been infected with the virus. Kidney transplant, as opposed to tissue transplant, is not an elective surgery, so the question raised is whether to do it or not. We present the case of a hyper-immunized 47-year-old male patient with end-stage chronic kidney disease who received a second kidney transplant, despite having a mild SARS-COV 2 infection just 2 weeks before his transplantation surgery. Frontiers Media S.A. 2023-03-23 /pmc/articles/PMC10076652/ /pubmed/37035338 http://dx.doi.org/10.3389/fmed.2023.1147835 Text en Copyright © 2023 Antal, Daciana Elec, Muntean, Moisoiu, Melinte and Elec. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Antal, Oana
Daciana Elec, Alina
Muntean, Adriana
Moisoiu, Tudor
Melinte, Razvan Marian
Elec, Florin Ioan
The immunologically high-risk kidney recipient in the early post-COVID-19 period. To do or not to do? A case report
title The immunologically high-risk kidney recipient in the early post-COVID-19 period. To do or not to do? A case report
title_full The immunologically high-risk kidney recipient in the early post-COVID-19 period. To do or not to do? A case report
title_fullStr The immunologically high-risk kidney recipient in the early post-COVID-19 period. To do or not to do? A case report
title_full_unstemmed The immunologically high-risk kidney recipient in the early post-COVID-19 period. To do or not to do? A case report
title_short The immunologically high-risk kidney recipient in the early post-COVID-19 period. To do or not to do? A case report
title_sort immunologically high-risk kidney recipient in the early post-covid-19 period. to do or not to do? a case report
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076652/
https://www.ncbi.nlm.nih.gov/pubmed/37035338
http://dx.doi.org/10.3389/fmed.2023.1147835
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