Cargando…

Case report: A relatively rare adverse event caused by carbetocin— placenta interception

Placenta interception is extremely rare, and herein, we report the case of a 33-year-old woman with placenta interception during cesarean section caused by carbetocin, which was intravenously injected immediately after delivery of the infant to prevent postpartum hemorrhage. There was no sign of pla...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jun-Qiang, Zhan, Yong-Chi, Wang, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076695/
https://www.ncbi.nlm.nih.gov/pubmed/37033610
http://dx.doi.org/10.3389/fphar.2023.1112694
_version_ 1785020189006364672
author Li, Jun-Qiang
Zhan, Yong-Chi
Wang, Xiao-Dong
author_facet Li, Jun-Qiang
Zhan, Yong-Chi
Wang, Xiao-Dong
author_sort Li, Jun-Qiang
collection PubMed
description Placenta interception is extremely rare, and herein, we report the case of a 33-year-old woman with placenta interception during cesarean section caused by carbetocin, which was intravenously injected immediately after delivery of the infant to prevent postpartum hemorrhage. There was no sign of placental separation in the third stage of labor. A protuberance with gross subserous blood vessels in the left fundus of the uterus was detected and was misdiagnosed as placental accreta. The patient was transferred to the district referral hospital to manage the protuberance after stitching up the incision. On opening the original incision in the tertiary hospital, the protuberance disappeared, and the placenta was found in the lower segment of the uterus cavity. The intercepted placenta showed a spontaneous resolution from the uterine wall and was removed intact. This case report details the typical presentation of placenta interception to make obstetricians aware of the possibility that carbetocin might lead to this adverse event.
format Online
Article
Text
id pubmed-10076695
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-100766952023-04-07 Case report: A relatively rare adverse event caused by carbetocin— placenta interception Li, Jun-Qiang Zhan, Yong-Chi Wang, Xiao-Dong Front Pharmacol Pharmacology Placenta interception is extremely rare, and herein, we report the case of a 33-year-old woman with placenta interception during cesarean section caused by carbetocin, which was intravenously injected immediately after delivery of the infant to prevent postpartum hemorrhage. There was no sign of placental separation in the third stage of labor. A protuberance with gross subserous blood vessels in the left fundus of the uterus was detected and was misdiagnosed as placental accreta. The patient was transferred to the district referral hospital to manage the protuberance after stitching up the incision. On opening the original incision in the tertiary hospital, the protuberance disappeared, and the placenta was found in the lower segment of the uterus cavity. The intercepted placenta showed a spontaneous resolution from the uterine wall and was removed intact. This case report details the typical presentation of placenta interception to make obstetricians aware of the possibility that carbetocin might lead to this adverse event. Frontiers Media S.A. 2023-03-23 /pmc/articles/PMC10076695/ /pubmed/37033610 http://dx.doi.org/10.3389/fphar.2023.1112694 Text en Copyright © 2023 Li, Zhan and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Li, Jun-Qiang
Zhan, Yong-Chi
Wang, Xiao-Dong
Case report: A relatively rare adverse event caused by carbetocin— placenta interception
title Case report: A relatively rare adverse event caused by carbetocin— placenta interception
title_full Case report: A relatively rare adverse event caused by carbetocin— placenta interception
title_fullStr Case report: A relatively rare adverse event caused by carbetocin— placenta interception
title_full_unstemmed Case report: A relatively rare adverse event caused by carbetocin— placenta interception
title_short Case report: A relatively rare adverse event caused by carbetocin— placenta interception
title_sort case report: a relatively rare adverse event caused by carbetocin— placenta interception
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10076695/
https://www.ncbi.nlm.nih.gov/pubmed/37033610
http://dx.doi.org/10.3389/fphar.2023.1112694
work_keys_str_mv AT lijunqiang casereportarelativelyrareadverseeventcausedbycarbetocinplacentainterception
AT zhanyongchi casereportarelativelyrareadverseeventcausedbycarbetocinplacentainterception
AT wangxiaodong casereportarelativelyrareadverseeventcausedbycarbetocinplacentainterception